FB2024_03 , released June 25, 2024
Aberration: Dmel\Df(2R)Egfr18
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General Information
Symbol
Df(2R)Egfr18
Species
D. melanogaster
Name
Deficiency (2R) Epidermal growth factor
FlyBase ID
FBab0001958
Feature type
chromosomal_deletion
Also Known As
Df(2R)top18A
Computed Breakpoints include

57E4-57E11;57F1

Features within 57E4--57F1
Sequence coordinates
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
Mutagen
gamma ray
Class of aberration (relative to wild type)
chromosomal_deletion
(FlyBase, 2007)
Class of aberration (relative to progenitor)
chromosomal_deletion
(Price et al., 1989)
Breakpoints

57E4-57E11;57F1

(Price et al., 1989)
Causes alleles
Egfrtop-18A
(Schnorr and Berg, 1996, Roth et al., 1995, Baker and Rubin, 1992, Price et al., 1989)
Carries alleles
Transposon Insertions
Formalized genetic data

l(2)57Db << bk1 << bk2 hits Egfr

Genetic mapping information
Comments
Comments on Cytology

Limits of break 1 from polytene analysis (FBrf0049331) Left limit of break 2 from inclusion of Egfr (FBrf0049331) Right limit of break 2 from polytene analysis (FBrf0049331)

Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
Egfr
(Price et al., 1997, Baumann and Skaer, 1993, Price et al., 1989)
Partially deleted / disrupted
Molecular Data
Completely deleted
Partially deleted
Genes NOT Deleted / Disrupted
Complementation Data
 
l(2)57Db
(Price et al., 1989)
l(2)57Eb
(Price et al., 1989)
Molecular Data
 
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location (0)
    If no genes are listed here, it may be because the affected region is very large. The JBrowse insert above may show an error for the same reason, and other FlyBase tools such as CytoSearch may also fail for large regions. You can contact FlyBase for more help.
    In this case, the "Export to Hitlist" button at left will also be disabled.
    Phenotypic Data
    In combination with other aberrations
    NOT in combination with other aberrations

    Mutations of H, vn, gro, E(Egfr)B56, E(Egfr)C12 or E(Egfr)C22 cause a mutant wing phenotype: thinning or gaps in wing vein L4.

    (Price et al., 1997)

    Most Egfrt1/Df(2R)Egfr18 heterozygous embryos have one fused dorsal appendage at the dorsal midline, few have a posterior micropyle and about half contain embryos.

    (Roth et al., 1995)

    Malpighian tubules in homozygous embryos are four small outpushings of the posterior hindgut, posterior tubules are more strongly affected than the anterior.

    (Baumann and Skaer, 1993)
    Stocks (2)
    Notes on Origin
    Discoverer
     
    Balancer / Genotype Variants of the Aberration
     
    Separable Components
     
    Other Comments
     
    Synonyms and Secondary IDs (8)
    Reported As
    Symbol Synonym
    Df(2R)Egfr18
    Df(2R)Egfr18A
    Df(2R)Egfr18
    (Hannan et al., 2006)
    Df(2R)Egfr18A
    Df(2R)top18A
    (Lesokhin et al., 1999, Kraut and Campos-Ortega, 1996, Neuman-Silberberg and Schupbach, 1996, Roth et al., 1995, Baumann and Skaer, 1993, Neuman-Silberberg and Schupbach, 1993, Baker and Rubin, 1992, Clifford and Schupbach, 1992, Price et al., 1989)
    Df(2R)topc18a
    (Goentoro et al., 2006)
    Egfr18
    (Sinenko et al., 2011, Sinenko et al., 2011)
    Name Synonyms
    Deficiency (2R) Epidermal growth factor
    Secondary FlyBase IDs
      References (18)