FB2024_03 , released June 25, 2024
Recombinant Construct: P{UAS-HsapTOR1A.ΔE.W}
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General Information
Symbol
P{UAS-Hsap\TOR1A.ΔE.W}
FlyBase ID
FBtp0116080
Feature type
transgenic_transposable_element
Component Allele(s)
Hsap\TOR1AΔE.UAS.cWa
Size
Expression Data
Associated insertion(s)
0 available
Molecular map
Description and Uses
Construct components
Component allele Hsap\TOR1AΔE.UAS.cWa
Transgenic product class
dominant_negative_variant
(Wakabayashi-Ito et al., 2015)
inframe_deletion
(Wakabayashi-Ito et al., 2015)
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Hsap\TOR1A
Description

UASt regulatory sequences drive expression of Hsap\TOR1A carrying a 3bp deletion that removes the E302/303 residue. This lesion is associated with autosomal dominant torsion dystonia-1. The protein acts as a dominant negative in flies.

(Wakabayashi-Ito et al., 2015)
Sequence Data
Sequence (FB)
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA Sequence
Extent
Segments and Size
Total Size
Left end
Right end
 
Segments
Num
Orientation
Symbol
Reference
Phenotypic Data
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Progenitors and Descendants
progenitor(s)
descendant(s)
Comments
Stocks (0)
Stocks containing insertion(s) of this recombinant construct
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
P{UAS-Hsap\TOR1A.ΔE.W}
(FlyBase, 1992-)
UAS-htorsinAΔE
(Wakabayashi-Ito et al., 2015)
Secondary FlyBase IDs
    References (2)