FB2024_03 , released June 25, 2024
Recombinant Construct: P{GABA-B-R2-GAL4.R}
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General Information
Symbol
P{GABA-B-R2-GAL4.R}
FlyBase ID
FBtp0053415
Feature type
transgenic_transposable_element
Component Allele(s)
Scer\GAL4GABA-B-R2.PR
Also Known As
GABABR2-Gal4, GABA-B-R2-GAL4
Size
Expression Data
GAL4 reporter/driver
Associated insertion(s)
0 available
Molecular map
Description and Uses
Construct components
Component allele Scer\GAL4GABA-B-R2.PR
Transgenic product class
Component
Use(s)
Regulatory region(s)
GABA-B-R2_GABABR2-Gal4
Encoded product / tool
GAL4
Description

1.5kb of genomic DNA immediately upstream of the GABA-B-R2 gene is cloned upstream of GAL4 driver coding sequences.

(Root et al., 2008)
Sequence Data
Sequence (FB)
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA Sequence
Extent
Segments and Size
Total Size
Left end
Right end
 
Segments
Num
Orientation
Symbol
Reference
Phenotypic Data
Expression Data
Reporter Expression
distribution deduced from reporter (Gal4 UAS)
Stage
Tissue/Position (including subcellular localization)
Reference
adult stage
adult insulin secreting cell of pars intercerebralis | subset
(Enell et al., 2010)
adult pars intercerebralis
(Enell et al., 2010)
adult brain | restricted
(Enell et al., 2010)
adult antennal lobe | restricted
(Root et al., 2008)
ellipsoid body outer central domain | restricted
(Kahsai et al., 2012)
ellipsoid body outer posterior domain | restricted
(Kahsai et al., 2012)
protocerebral bridge | restricted
(Kahsai et al., 2012)
bulb | restricted
(Kahsai et al., 2012)
fan-shaped body | restricted
(Kahsai et al., 2012)
Additional Information
Statement
Reference

ScerGAL4GABA-B-R2.PR drives expression in the ellipsoid body ring between the innervation regions of R3 and R4d ring neurons and also in the R3 ring. Expression is also detected in the fan-shaped body dorsal and central layers (whereas GABA-B-R2 protein is expressed in all layers), in the protocerebral bridge and bulb (lateral triangle).

(Kahsai et al., 2012)

ScerGAL4GABA-B-R2.PR drives expression in the insulin producing cells (IPC), a subset of the median neurosecretory cells of the pars intercerebralis and in other cells located ventrally to the IPC cells that are part of the median neurosecretory cluster. Most, if not all, IPC cells labeled with ScerGAL4GABA-B-R2.PR also express Ilp2 protein.

(Enell et al., 2010)
 
Marker for
Reflects expression of
GABA-B-R2
(Kahsai et al., 2012, Enell et al., 2010, Root et al., 2008)
Reporter construct used in assay
Progenitors and Descendants
progenitor(s)
descendant(s)
Comments
Stocks (0)
Stocks containing insertion(s) of this recombinant construct
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (9)
Reported As
Symbol Synonym
GABA-B-R2-GAL4
(Rajan and Perrimon, 2012)
GABA-B-R2-Gal4
(Wilson et al., 2020)
GABABR2-GAL4
(Kahsai et al., 2012)
GABABR2-Gal4
(Enell et al., 2010, Root et al., 2008)
GBR-Gal4
(Enell et al., 2010)
GBR2-G4
(Kahsai et al., 2012)
GBR2-Gal4
(Enell et al., 2010)
P{GABA-B-R2-GAL4.R}
(FlyBase, 1996-)
P{GABA-B-R2-GAL4}
(FlyBase, 1992-)
Secondary FlyBase IDs
    References (8)