FlyBase Recombinant Construct Report: P{UAS-PKA.mC}

General Information

Symbol

P{UAS-PKA.mC}

FlyBase ID

FBtp0001143

Feature type

transgenic_transposable_element

Component Allele(s)

Mmus\Prkaca^mC.UAS

Also Known As

UAS-mC*, UAS-PKA^CA, UAS-PKAact¹, UAS-mc^*, UAS-PKAmc*, UAS-PKA-mc*, mC*

Size

Expression Data

Associated insertion(s)

0 available

Molecular map

Description and Uses

Construct components

Component allele Mmus\Prkaca^mC.UAS

Transgenic product class

missense_variant

(Li et al., 1995)

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

Mmus\Prkaca

Also carries

FRT

recombinase target site

Description

The FRT cassette has been excised, allowing UAS regulatory sequences to drive expression of a constitutively active form of Mmus\Prkaca ('mC*', contains the amino acid replacements H87Q and W196R).

(Li et al., 1995)

Sequence Data

Sequence (FB)

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA Sequence

Extent

Segments and Size

Total Size

Left end

Right end

Segments

Num

Orientation

Symbol

Reference

Phenotypic Data

Component Allele

Phenotypic Data

Mmus\Prkaca^mC.UAS

Phenotypic Class Phenotype Manifest In Detailed Description

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Progenitors and Descendants

progenitor(s)

descendant(s)

Comments

report comment: The mouse PKA allele carried in this construct is constitutively active (reduced binding to regulatory subunit).PKA coding sequence terminates with human growth hormone polyA signal.

(Li et al., 1995)

Stocks (0)

Stocks containing insertion(s) of this recombinant construct

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (31)

Reported As

Symbol Synonym

5xUAS-PKA*

(Walker et al., 2013)

CA-PKA

(Cho et al., 2015)

GAL4 UAS-mC*

(Li et al., 1995)

MC*

(Jiang et al., 2014)

PKA-CA

(Yoshihara et al., 2005)

PKA^ACT

(Sulkowski et al., 2014)

PKA^CA

(Hong et al., 2008)

PKAact

(Chyb et al., 1999)

Pka-C*

(Jackson and Berg, 2002)

P{UAS-PKA.mC}

(FlyBase, 1996-)

UAS-CA-PKA

(Copf, 2014)

UAS-PKA-C1-mC*

(Thornquist et al., 2021)

UAS-PKA-mC*

(Thornquist et al., 2021)

UAS-PKA-mc*

(Copf, 2014)

UAS-PKA.mC

(Sulkowski et al., 2014)

UAS-PKA^*

(Hoxha et al., 2013)

UAS-PKA^CA

(Hao et al., 2016, Kang et al., 2011, Lee et al., 2009, Hong et al., 2008)

UAS-PKA^act

(Zhao et al., 2020)

UAS-PKAact¹

(Baines, 2004, Mee et al., 2004, Baines, 2003)

UAS-PKAmC

(Shulman and Feany, 2003)

UAS-PKAmC*

(Wolterhoff et al., 2020)

UAS-PKAmc*

(Yang et al., 2009)

UAS-constitutively active PKA

(Lee et al., 2009)

UAS-mC*

(Li et al., 2014, Liu et al., 2012, Jia et al., 2009, Smelkinson and Kalderon, 2006, Zhou et al., 2006, Jia et al., 2005, Zhang et al., 2005, Jia et al., 2004, Kimura et al., 2004, Dai et al., 2003, Ou et al., 2002, Price and Kalderon, 2002, Venkatesh et al., 2001, Price and Kalderon, 1999, Wang et al., 1999)

UAS-mC^*

(Cheng et al., 2012, Liu et al., 2007)

UAS-mc*

(Lee et al., 2009, Jia et al., 2002)

UAS-mc^*

(Joiner et al., 2006)

UAS::mPKA*

(Kupinski et al., 2013)

UASmPkaC1*

(Li et al., 2021)

UASmc^*

(Pitman et al., 2006)

mC*

(Chen et al., 2017)

Secondary FlyBase IDs

References (49)

Report Sections

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