FB2024_03 , released June 25, 2024
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Marygold, S.J. (2020.2.14). D. melanogaster OST subunits. 
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FBrf0244946
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Personal communication to FlyBase
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The oligosaccharyltransferase complex (OST) is an evolutionary conserved multi-protein complex that catalyzes the addition of glycans to selected Asn residues within nascent polypeptides in the lumen of the endoplasmic reticulum (reviewed by Harada et al 2019; PMID:31810196). Mammalian cells express two distinct OST complexes that contain STT3A or STT3B as the catalytic subunit and several accessory proteins: six common subunits, two STT3A-OST-specific subunits and two STT3B-OST-specific subunits (PMID:3181019). The OST complex has not yet been studied in detail in Drosophila melanogaster, though Yamamoto-Hino et al 2015 (FBrf0228609) listed 7 subunits: CG33303, Dad1, Ost48, OstDelta, Ostgamma, Stt3A and Stt3B.
I used 3 additional sources to compile a full list of candidate D. melanogaster OST subunits:
1. Current Gene Ontology (GO) annotations to fly genes using the terms "oligosaccharyltransferase complex" (GO:0008250) and "dolichyl-diphosphooligosaccharide-protein glycotransferase activity" (GO:0004579).
2. D. melanogaster orthologs of human OST subunits (determined using the DIOPT tool) described in PMID:31810196.
3. D. melanogaster orthologs of human OST subunits (determined using the HCOP tool) listed in the OST gene group at the HGNC site (https://www.genenames.org/data/genegroup/#!/group/445)
The resulting list of 11 D. melanogaster genes is:
FBgn	gene_sym	human_ortholog
FBgn0031149	Stt3A	STT3A
FBgn0011336	Stt3B	STT3B
FBgn0053303	CG33303	RPN1
FBgn0034277	OstDelta	RPN2
FBgn0036667	kud	TMEM258
FBgn0263852	Dad1	DAD1
FBgn0014868	Ost48	DDOST
FBgn0053774	CG33774	OST4
FBgn0031529	CG9662	OSTC
FBgn0051460	CG31460	KRTCAP2
FBgn0032015	Ostgamma	TUSC3/MAGT1
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    English
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    Gene Groups (1)
    Genes (11)