Manning, S.A., Harvey, K.F. (2015). Warts Opens Up for Activation.  Dev. Cell 35(6): 666--668.

FBrf0232302

Note

Warts is the central effector kinase of the Hippo growth-control pathway. In this issue of Developmental Cell, by assessing Warts conformation in vivo, Vrabioiu and Struhl (2015) report that the Mob family protein Mats regulates Warts activity allosterically, independent of phosphorylation by Hippo.