FB2024_03 , released June 25, 2024
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Citation
Kim, M., Fong, C.S., Tsou, M.F. (2014). Centriole duplication: when PLK4 meets Ana2/STIL.  Curr. Biol. 24(21): R1046--R1048.
FlyBase ID
FBrf0229102
Publication Type
Note
Abstract
Polo-like kinase 4 is known to drive centriole duplication, but the relevant substrate remains elusive. A new study shows that PLK4 phosphorylates a key centriolar component, Ana2/STIL, to initiate centriole assembly.
PubMed ID
25517369
PubMed Central ID
DOI
10.1016/j.cub.2014.09.079
Related Publication(s)
Research paper

Plk4 phosphorylates ana2 to trigger sas6 recruitment and procentriole formation.
Dzhindzhev et al., 2014, Curr. Biol. 24(21): 2526--2532 [FBrf0226888]

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Secondary IDs
    Language of Publication
    English
    Additional Languages of Abstract
    Parent Publication
    Publication Type
    Journal
    Abbreviation
    Curr. Biol.
    Title
    Current Biology
    Publication Year
    1991-
    ISBN/ISSN
    0960-9822
    Data From Reference