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Citation
Wang, J.T., Barres, B.A. (2012). Axon degeneration: where the Wlds things are.  Curr. Biol. 22(7): R221--R223.
FlyBase ID
FBrf0219143
Publication Type
Note
Abstract
Expression of the Wld(s) protein significantly delays axon degeneration in injuries and diseases, but the mechanism for this protection is unknown. Two recent reports present evidence that axonal mitochondria are required for Wld(S)-mediated axon protection.
PubMed ID
22497934
PubMed Central ID
PMC4449840 (PMC) (EuropePMC)
DOI
10.1016/j.cub.2012.02.056
Related Publication(s)
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A novel Drosophila model of nerve injury reveals an essential role of nmnat in maintaining axonal integrity.
Fang et al., 2012, Curr. Biol. 22(7): 590--595 [FBrf0218051]

Wld(S) Prevents Axon Degeneration through Increased Mitochondrial Flux and Enhanced Mitochondrial Ca(2+) Buffering.
Avery et al., 2012, Curr. Biol. 22(7): 596--600 [FBrf0218040]

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Secondary IDs
    Language of Publication
    English
    Additional Languages of Abstract
    Parent Publication
    Publication Type
    Journal
    Abbreviation
    Curr. Biol.
    Title
    Current Biology
    Publication Year
    1991-
    ISBN/ISSN
    0960-9822
    Data From Reference