FB2024_03 , released June 25, 2024
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Citation
Kramer, H. (2001). Neuralized: regulating notch by putting away delta.  Dev. Cell 1(6): 725--726.
FlyBase ID
FBrf0141464
Publication Type
Note
Abstract
Neuralized acts in a subset of Notch-dependent cell fate decisions including lateral inhibition in Drosophila neurogenesis. Three recent papers reveal that Neuralized acts as a ubiquitin ligase and triggers endocytosis of the ligand Delta.
PubMed ID
PubMed Central ID
Related Publication(s)
Research paper

neuralized encodes a peripheral membrane protein involved in delta signaling and endocytosis.
Pavlopoulos et al., 2001, Dev. Cell 1(6): 807--816 [FBrf0144791]

Drosophila neuralized is a ubiquitin ligase that promotes the internalization and degradation of delta.
Lai et al., 2001, Dev. Cell 1(6): 783--794 [FBrf0141465]

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Secondary IDs
    Language of Publication
    English
    Additional Languages of Abstract
    Parent Publication
    Publication Type
    Journal
    Abbreviation
    Dev. Cell
    Title
    Developmental Cell
    Publication Year
    2001-
    ISBN/ISSN
    1534-5807 1878-1551
    Data From Reference
    Genes (5)