Pardue, M.L., Bendena, W.G., Fini, M.E., Garbe, J.C., Hogan, N.C., Traverse, K.L. (1990). Hsr-Omega, a novel gene encoded by a Drosophila heat shock puff.  Biol. Bull., Wood's Hole 179(1): 77--86.

FBrf0051277

Review

Although originally identified because of its abundant transcription in heat shock, the hsr-omega gene is active, at generally lower levels, in non-stressed cells. The locus produces an unusual set of three transcripts. Evidence from a variety of experiments suggests that one of these transcripts acts in the nucleus, possibly to regulate the activity of a nuclear protein. Another of the transcripts appears to act in the cytoplasm, possibly monitoring or regulating some aspect of translation. The two transcripts together could have a role in coordinating nuclear and cytoplasmic activity. A number of processes occur in eukaryotic cells in which nuclear and cytoplasmic activities need to be coordinated; we suggest that hsr-omega plays a role in such coordination.