FB2024_03 , released June 25, 2024
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
rod, Zwilch
FlyBase ID
FBig0000104151
Interaction Network
Interactions Browser links
rod network
Zwilch network
esyN Network Diagram
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Protein
RNA
Selected Interactor(s)
Common Interactor(s)
Reported Interactions
FBrf0159187-8.coIP.MS
Reference
Williams et al., 2003
Description
physical association
Assay
Collection
Source/Stage
organism / embryonic stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Zwilch 

Zwilch

bait
rod 

ROD

prey

250kDa band

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was embryos of wild-type fly line; bait produced from endogenous gene; prey produced from endogenous gene.

(Williams et al., 2003)

Zw10, rod, Zwilch and Hsc70-4 copurify in roughly equal stoichiometries.

(Williams et al., 2003)
FBrf0227800-2.coIP.WB
Reference
Défachelles et al., 2015
Description
physical association
Assay
Collection
Source/Stage
organism / embryonic stage 1embryonic stage 4embryonic stage 3embryonic cycle 6embryonic cycle 5embryonic cycle 8embryonic cycle 7embryonic cycle 3embryonic cycle 4embryonic cycle 9embryonic stage 2
Cell line used
Participants
Corresponds to
Reported as
Role
Note
rod 

Rod

bait
Zwilch 

Zwilch

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was embryos of wild-type fly line; bait produced from endogenous gene; prey produced from endogenous gene.

(Défachelles et al., 2015)
FBrf0247450-3.coIP.WB
Reference
Menant and Karess, 2020
Description
physical association
Assay
Collection
Source/Stage
brain / third instar larval stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
rod 

Rod

bait

RFP tag

Zwilch 

Zwilch

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was brains of transgenic larvae; bait produced from tagged transgenic construct; prey produced from endogenous gene.

(Menant and Karess, 2020)
FBrf0247450-6.CM.MW
Reference
Menant and Karess, 2020
Description
physical association
Assay
Collection
Source/Stage
brain / third instar larval stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
rod 

Rod

neutral component

RFP tag

rod 

Rod

neutral component

RFP tag

rod 

Rod

neutral component

RFP tag

Zwilch 

Zwilch

neutral component
Zwilch 

Zwilch

neutral component
Zwilch 

Zwilch

neutral component
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Ternary rod-Zw10-Zwilch complex captured as 3 binary interactions. Detection of the ternary complex requires a rod and Zw10 wild-type background.

(Menant and Karess, 2020)

Source was brains of transgenic larvae; proteins produced from tagged transgenic construct or endogenous gene.

(Menant and Karess, 2020)
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (3)