FB2024_03 , released June 25, 2024
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
Eps-15, lqf
FlyBase ID
FBig0000098391
Interaction Network
Interactions Browser links
Eps-15 network
lqf network
esyN Network Diagram
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Protein
RNA
Selected Interactor(s)
Common Interactor(s)
Reported Interactions
FBrf0202144-5.coIP.WB
Reference
Koh et al., 2007
Description
physical association
Assay
Collection
Source/Stage
adult head / adult stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Eps-15 

Eps15-XP

bait
lqf 

Epsin/Lqf

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was adult heads of wild-type fly line; bait produced from endogenous gene; prey produced from endogenous gene.

(Koh et al., 2007)
FBrf0217494-3.PD.WB
Reference
Xie et al., 2012
Description
physical association
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Eps-15 

Eps-15

bait

GST tag

Eps-15 
lqf 

lqf

prey

MBP tag

lqf 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Eps-15 
EF Hand domain
sufficient binding region
aa 1-515

coordinates relative to Eps-15-PA

lqf 
NPF domain
necessary binding region
aa 567-638

coordinates relative to lqf-PF

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Interaction in vitro; bait produced as a recombinant fusion protein in bacterial system; prey produced as a recombinant fusion protein in bacterial system.

(Xie et al., 2012)
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (2)