FB2024_03 , released June 25, 2024
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
tyf, tim
FlyBase ID
FBig0000097458
Interaction Network
Interactions Browser links
tyf network
tim network
esyN Network Diagram
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Protein
RNA
Selected Interactor(s)
Common Interactor(s)
Reported Interactions
FBrf0213059-6.coIP.PCR
Reference
Lim et al., 2011
Description
physical association
Assay
Collection
Source/Stage
adult head / adult stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
tyf 

TYF

bait

V5 tag

tim 

tim

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was adult head of transgenic fly line; bait produced from tagged transgenic construct; prey produced from endogenous gene.

(Lim et al., 2011)

tyf protein can stimulate translation of bound transcripts.

(Lim et al., 2011)
FBrf0221600-11.coIP.PCR
Reference
Lim and Allada, 2013
Description
physical association
Assay
Collection
Source/Stage
adult head / adult stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
tyf 

TYF

bait

FLAG tag

tyf 
tim 

tim

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
tyf 
N-terminal region
sufficient binding region
aa 1-1624

\'TYF-ΔC5\'

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was adult head of transgenic fly line; bait produced from tagged transgenic construct; prey produced from endogenous gene.

(Lim and Allada, 2013)

The pAbp-interacting motif is dispensable for the interaction of tyf with target transcripts.

(Lim and Allada, 2013)
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (2)