Please see the JBrowse view of Dmel\Fuca for information on other features
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AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.
Gene model reviewed during 6.02
Gene model reviewed during 5.45
Gene model reviewed during 5.43
Gene model reviewed during 6.05
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Fuca using the Feature Mapper tool.
The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).
Fuca transcripts are detected by RT-PCR in the male testis, accessory gland, ejaculatory bulb, ejaculatory duct, and brain. Similar levels are found in the female brain. Lower levels are found in ovary and midgut. On northern blots, the long Fuca transcript is present in all samples while the shorter transcript is observed in brain. In situ hybridization on male reproductive apparatus shows weak expression in spermatogonia, and more robust expression from premeiotic spermatocytes up to round spermatids. Low levels are seen in elongating spermatid cysts. No expression is seen in stem cells. Expression is also observed in the terminal epithelium of the testis, and in the epithelium of seminal vesicles, male accessory glands, and ejaculatory duct. In ovaries, strong expression is observed in nurse cells from stage 1-10 and absent from the oocyte. Weak expression is seen at stages 12-14 in the nurse apical cluster.
JBrowse - Visual display of RNA-Seq signals
View Dmel\Fuca in JBrowse3-36
3-30.0
3-35.5
Mapping based on 45 recombinants between h and st.
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
polyclonal
Expression is enriched in embryonic gonads.
α-fucosidase dosage sensitive regions mapped, by segmental aneuploidy, to 52E--54F and 88C--91B. Their relationship to Fuc is not clear.
Source for merge of: Fuca Fuc
One or more of the processed transcripts for these genes contain two non-overlapping open reading frames (ORFs). The non-overlapping ORFs are represented by CG6128 (FBgn0036169), CG11714 (FBgn0036170).
Dicistronic annotation CG33047 split out into separate annotations for each open reading frame, CG11714 and CG6128, in release 4.2 of the genome annotation.
Source for identity of: Fuca CG6128
