TepII, dTEPII, Tep II, Thiolester containing protein II
Please see the JBrowse view of Dmel\Tep2 for information on other features
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AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.
Low-frequency RNA-Seq exon junction(s) not annotated.
Gene model reviewed during 5.47
None of the polypeptides share 100% sequence identity.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Tep2 using the Feature Mapper tool.
The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).
Tep2 expression is detected in plasmatocytes and in fat body in larvae. In adults it is observed in the crop epithelium and in the epidermis underlying the cuticle in the abodomen but only on the ventral side.
JBrowse - Visual display of RNA-Seq signals
View Dmel\Tep2 in JBrowse2-28
2-24.9
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
S2 cells treated with dsRNA generated against this gene show reduced phagocytosis of Escherichia coli compared to untreated cells. However, the dsRNA treatment does not affect phagocytosis of Candida albicans or Staphylococcus aureus.
Identified as a gene with significant level of mRNA cycling as assessed by expression analysis using high density oligonucleotide arrays with probe generated from adult heads harvested over six time points over the course of a day. Shows alteration in expression in a Clk mutant background.
Source for merge of: TepII CG7052
Source for merge of: TepII CG18589
Annotations CG7052 and CG18589 merged as CG7052 in release 3 of the genome annotation.
Source for merge of TepII CG7052 was sequence comparison ( date:000423 ).
Source for identity of: Tep2 TepII