p21, Hsap\p21
Foreign sequence; species == Homo sapiens; gene == CDKN1A; HGNC:1784.
Up-to-date information on gene product function can be found by searching UniProtKB for proteins or RNAcentral for non-coding RNAs.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Hsap\CDKN1A using the Feature Mapper tool.
The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).
JBrowse - Visual display of RNA-Seq signals
View Hsap\CDKN1A in JBrowsePlease Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Cyclin-dependent kinase inhibitor.
Expression of Hsap\CDKN1A has been used to block the second mitotic wave in the developing eye. Each cell type is still specified, hence cell fate determination is regulated independently of the division pattern of the precursor cells.
FlyBase curator comment: Name changed to reflect current HGNC name (19th Nov. 2012).