Up-to-date information on gene product function can be found by searching UniProtKB for proteins or RNAcentral for non-coding RNAs.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dhyd\ftz using the Feature Mapper tool.
The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).
JBrowse - Visual display of RNA-Seq signals
View Dhyd\ftz in JBrowsePlease Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Dhyd\ftz has been cloned and sequenced and compared with D.melanogaster ftz. The pattern of Dhyd\ftz expression during early embryonic development has been compared with the pattern of early embryonic D.melanogaster ftz expression.
DNA elements both 3' and 5' to the coding region that are important in proper regulation of expression are the most evolutionarily conserved regions in the vicinity of gene homologs.
The D.melanogaster ftz autoregulatory domain, AE, is a direct target for the ftz homeodomain gene product. Deletion analysis defines multiple elements redundantly involved in enhancer activity. Several of these elements are conserved in the AE homologs of D.virilis and D.hydei and in the developmentally regulated eve and Ubx genes.
Dhyd\ftz has been cloned and sequenced. Comparison with D.melanogaster ftz shows that the overall organisation of the gene is similar in both species. Dhyd\ftz is inverted in the Antp in D.hydei compared to D.melanogaster.