FlyBase Gene Report: Dmel\ec

General Information

Symbol

Dmel\ec

Species

D. melanogaster

Name

echinus

Annotation Symbol

CG2904

Feature Type

protein_coding_gene

FlyBase ID

FBgn0000542

Gene Model Status

Current

Stock Availability

51 publicly available

Gene Summary

echinus (ec) encodes a protein phosphatase 1 (PP1) binding protein involved in interommatidial cell sorting and cell death. [Date last reviewed: 2019-07-11] (FlyBase Gene Snapshot)

All Summaries

Gene Snapshot
Alliance
Auto summary
Gene Group
Red Book
Interactive Fly

Also Known As

EG:EG0002.3

Key Links

Genomic Location

Cytogenetic map

3F2-3F3

Sequence location

X:3,811,698..3,857,621 [+]

Recombination map

1-5

RefSeq locus

NC_004354 REGION:3811698..3857621

Sequence

Get Decorated FASTA

Genomic Maps

JBrowse

Other Genome Views

The following external sites may use different assemblies or annotations than FlyBase.

Function

Gene Ontology (GO) Annotations (6 terms)

Molecular Function (3 terms)

Terms Based on Experimental Evidence (2 terms)

CV Term

Evidence

References

enables protein phosphatase 1 binding

inferred from physical interaction with FLYBASE:flw; FB:FBgn0000711

(Bennett et al., 2006)

inferred from physical interaction with FLYBASE:Pp1-13C; FB:FBgn0003132

(Bennett et al., 2006)

inferred from physical interaction with FLYBASE:Pp1α-96A; FB:FBgn0003134

(Bennett et al., 2006)

inferred from physical interaction with FLYBASE:Pp1-87B; FB:FBgn0004103

(Bennett et al., 2006)

NOT enables cysteine-type deubiquitinase activity

inferred from direct assay

(Copeland et al., 2007)

Terms Based on Predictions or Assertions (1 term)

CV Term

Evidence

References

NOT enables peptidase activity

inferred from key residues with MEROPS:C19.UNW

(GO curators, 2012-)

Biological Process (3 terms)

Terms Based on Experimental Evidence (3 terms)

CV Term

Evidence

References

involved_in compound eye retinal cell programmed cell death

inferred from mutant phenotype

(Montrasio et al., 2007)

involved_in ommatidial rotation

inferred from mutant phenotype

(Montrasio et al., 2007)

involved_in positive regulation of compound eye retinal cell programmed cell death

inferred from mutant phenotype

(Copeland et al., 2007)

Terms Based on Predictions or Assertions (0 terms)

Cellular Component (0 terms)

Terms Based on Experimental Evidence (0 terms)

Terms Based on Predictions or Assertions (0 terms)

Gene Group (FlyBase)

C19 NON-PEPTIDASE HOMOLOGS

Protein Family (UniProt)

Protein Signatures (InterPro)

Summaries

Gene Snapshot

echinus (ec) encodes a protein phosphatase 1 (PP1) binding protein involved in interommatidial cell sorting and cell death. [Date last reviewed: 2019-07-11]

Gene Group (FlyBase)

C19 NON-PEPTIDASE HOMOLOGS -: C19 non-peptidase homologs are similar in amino acid sequence to USP deubiquitinases (C19 cysteine peptidases) but lack one or more of the expected catalytic residues. (Adapted from FBrf0239469.)

Phenotypic Description (Red Book; Lindsley and Zimm 1992)

ec: echinus

Eyes large and bulging. Eye surface rough; facets large. Wings rather short and broad. Body thickset. Tends to remove dorsocentrals (posterior more than anterior) and posterior notopleurals; may also add dorsocentrals anterior to anterior dorsocentrals whether or not posterior bristles removed (Sturtevant). Reduces number of mesopleural hairs in h homozygotes (Sturtevant, 1969, Dev. Biol. 21: 48-61). ec is visible in +/ec/ec triploids (Gersh). RK1.

Gene Model and Products

Number of Transcripts

Number of Unique Polypeptides

Please see the JBrowse view of Dmel\ec for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)

Isoform displayed:

Pfam protein domains

InterPro name

classification

start

end

Protein Domains (via SMART)

Isoform displayed:

SMART protein domains

InterPro name

classification

start

end

Structure

Protein 3D structure (Predicted by AlphaFold) (AlphaFold entry Q1W9P9)

If you don't see a structure in the viewer, refresh your browser.

Model Confidence:

Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)

AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.

Experimentally Determined Structures

Crossreferences

Comments on Gene Model

Gene model reviewed during 5.52

Gene model reviewed during 5.42

Gene model reviewed during 5.55

Sequence Ontology: Class of Gene

nuclear_gene

protein_coding_gene

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Assoc. CDS (aa)

ec-RA

FBtr0070606

NM_166992

6759

1712

ec-RB

FBtr0112801

NM_130722

6863

1746

ec-RC

FBtr0112802

NM_001103407

6681

1765

Additional Transcript Data and Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

UniProt

RefSeq ID

GenBank

ec-PA

FBpp0100019

188.4

1712

8.88

FBpp0111713

192.0

1746

8.98

FBpp0111714

193.4

1765

9.21

Q1W9P9

NP_001096877

ABW09333

Polypeptides with Identical Sequences

None of the polypeptides share 100% sequence identity.

Additional Polypeptide Data and Comments

Reported size (kDa)

Comments

External Data

Crossreferences

InterPro - A database of protein families, domains and functional sites

Linkouts

Sequences Consistent with the Gene Model

Nucleotide / Polypeptide Records

UniProt

Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\ec using the Feature Mapper tool.

External Data

Crossreferences

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

Linkouts

Expression Data

Testis-specificity index

The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).

-0.43

Transcript Expression

in situ

Stage

Tissue/Position (including subcellular localization)

Reference

pupal stage

retina

(Copeland et al., 2007)

cone cell

(Copeland et al., 2007)

primary pigment cell

(Copeland et al., 2007)

interommatidial precursor cell

(Copeland et al., 2007)

Additional Descriptive Data

ec transcript is ubiquitously expressed at low uniform levels in the pupal retinal, and is detected in cone cells, primary pigment cells, and interommatidial cells.

(Copeland et al., 2007)

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Evidence

References

Expression Deduced from Reporters

Reporter: P{lacZ}ec^PlacZ

Stage

Tissue/Position (including subcellular localization)

Reference

pupal stage

retina

(Copeland et al., 2007)

cone cell

(Copeland et al., 2007)

primary pigment cell

(Copeland et al., 2007)

interommatidial precursor cell

(Copeland et al., 2007)

High-Throughput Expression Data

Associated Tools

JBrowse - Visual display of RNA-Seq signals

View Dmel\ec in JBrowse

RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region

View exonic expression by developmental stage for Dmel\ec

View exonic expression by tissue for Dmel\ec

Bulk Downloads

RNA-Seq RPKM values for all genes

Reference

See Gelbart and Emmert, 2013 for analysis details and data files for all genes.

Developmental Proteome: Life Cycle

Developmental Proteome: Embryogenesis

External Data and Images

Linkouts

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

31339/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0000542

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0000542

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0000542

Flygut - An atlas of the Drosophila adult midgut

FBgn0000542

Images

FlyBase Wiki

Image Based Resources

Alleles, Insertions, Transgenic Constructs, and Aberrations

Classical and Insertion Alleles ( 31 )

For All Classical and Insertion Alleles Show

Other relevant insertions

Transgenic Constructs ( 16 )

For All Alleles Carried on Transgenic Constructs Show

Transgenic constructs containing/affecting coding region of ec

Transgenic constructs containing regulatory region of ec

Aberrations (Deficiencies and Duplications) ( 71 )

Inferred from experimentation ( 71 )

Gene disrupted in

Gene duplicated in

Dp(1;1)105

(Dobzhansky, 1932)

Dp(1;3)DC067

(Popodi et al., 2010-, Venken et al., 2010)

(Dobzhansky, 1932)

(Lefevre, 1970)

(Hawley et al., 1992)

Gene not disrupted in

(Mackensen, 1935)

(Patterson, 1932)

(Patterson, 1932)

(Patterson, 1932)

(Patterson, 1932)

(Patterson, 1932)

(Oliver et al., 1988)

Df(1)C149

(Oliver et al., 1988)

Df(1)cho19

(Steinmann-Zwicky, 1988)

Df(1)cho^L1

(Goode et al., 1996)

Df(1)ED6712

(Montrasio et al., 2007)

Df(1)GA56

(Oliver et al., 1988)

Df(1)GA102

(Oliver et al., 1988)

Df(1)JC70

(Oliver et al., 1988, Schalet, 1986)

Df(1)N-8

(Mackensen, 1935)

Df(1)N-54l9

(Mohler, 1956)

Df(1)N73

(Oliver et al., 1988)

Df(1)N-264-58

(Demerec, 1940)

Df(1)N^55l

(Hillman, 1958)

Df(1)ovo6

(Oliver et al., 1988)

Df(1)ovo7

(Oliver et al., 1988)

Df(1)rb1

(Oliver et al., 1988)

Df(1)rb13

(Oliver et al., 1988)

Df(1)rb30

(Oliver et al., 1988)

Df(1)rb33

(Oliver et al., 1988)

Df(1)rb46

(Oliver et al., 1988)

Df(1)RC40

(Oliver et al., 1988, Craymer and Roy, 1980)

Df(1)Sp(rb)

(Schalet, 1986)

In(1)Cl^Lbb^DfR

T(1;3)N^34b

(Oliver, 1937)

Gene not duplicated in

Gene partially disrupted in

Df(1)ec^Δ9

(Copeland et al., 2007)

Inferred from location ( 0 )

Variants

Variant Molecular Consequences

Alleles Representing Disease-Implicated Variants

Phenotypes

For more details about a specific phenotype click on the relevant allele symbol.

Lethality

Allele

lethal - all die before end of pupal stage, with Scer\GAL4^dpp.PU

ec^KK101112

partially lethal, with Scer\GAL4^elav.PU

ec^KK101112

partially lethal, with Scer\GAL4^sqh.PW

ec^KK101112

viable

ec^spok

Other Phenotypes

Allele

abnormal pain response | third instar larval stage, with Scer\GAL4^ppk.1.9

ec^VDRC.cUa

abnormal sensory perception | third instar larval stage, with Scer\GAL4^ppk.1.9

ec^VDRC.cUa

decreased cell death | pupal stage P6

ec^spok

decreased cell death | pupal stage P7

short lived, with Scer\GAL4^elav.PU

ec^KK101112

short lived, with Scer\GAL4^sqh.PW

ec^KK101112

some die during pupal stage, with Scer\GAL4^dpp.PU

ec^KK101112

visible

visible (with Df(1)HC244)

ec^3c3

visible | recessive

wild-type

ec^EP1343

Phenotype manifest in

Allele

adult abdomen

ec¹

adult thorax

ec¹

cone cell

ec¹

dorsocentral bristle

ec¹

eye

eye (with Df(1)HC244)

ec^3c3

interommatidial precursor cell | pupal stage P6 | increased number

ec^spok

interommatidial precursor cell | pupal stage P7 | increased number

ommatidium

ommatidium (with Df(1)GA102)

ommatidium (with Df(1)HC244)

ec^spok

ommatidium (with ec¹)

ec^spok

ommatidium (with ec^KG09175)

ec^spok

ommatidium (with ec^KG10228)

ec^spok

ommatidium (with ec^spok)

ommatidium | pupal stage P6

ommatidium | pupal stage P7

posterior notopleural bristle

ec¹

primary pigment cell

ec¹

primary pigment cell precursor | pupal stage P6 | increased number

ec^spok

retina | pupal stage

wing

ec¹

Orthologs

Downloads

Download All DIOPT Orthologs

Human Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Homo sapiens (Human) (2)

Hsap\USP54

6 of 14

Yes

Hsap\USP53

5 of 14

Yes

Model Organism Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Rattus norvegicus (Norway rat) (2)

Rnor\Usp54

6 of 14

Yes

Rnor\Usp53

1 of 14

Yes

Mus musculus (laboratory mouse) (2)

Mmus\Usp53

6 of 14

Yes

Mmus\Usp54

6 of 14

Yes

Xenopus tropicalis (Western clawed frog) (3)

Xtro\usp53

5 of 13

Yes

Xtro\usp54

4 of 13

Yes

Xtro\ankfy1

1 of 13

Danio rerio (Zebrafish) (4)

Drer\usp54a

6 of 14

Yes

Drer\usp53b

5 of 14

Yes

Drer\LOC101885715

4 of 14

Yes

Drer\usp54b

3 of 14

Yes

Caenorhabditis elegans (Nematode, roundworm) (0)

Anopheles gambiae (African malaria mosquito) (1)

Agam\AgaP_AGAP000205

10 of 12

Yes

Arabidopsis thaliana (thale-cress) (21)

Atha\AT3G47890

6 of 13

Yes

Atha\AT3G47910

5 of 13

Yes

Atha\AT1G52430

2 of 13

Yes

Atha\AT1G52450

2 of 13

Yes

Atha\AT1G65110

2 of 13

Yes

Atha\AT1G65120

2 of 13

Yes

Atha\AT1G65130

2 of 13

Yes

Atha\AT1G65200

2 of 13

Yes

Atha\AT2G27630

2 of 13

Yes

Atha\AT2G27650

2 of 13

Yes

Atha\AT2G34230

2 of 13

Yes

Atha\AT2G34240

2 of 13

Yes

Atha\AT5G51530

2 of 13

Yes

Atha\AT5G61940

2 of 13

Yes

Atha\AT5G61950

2 of 13

Yes

Atha\MEE20

2 of 13

Yes

Atha\AT1G65140

1 of 13

Yes

Atha\AT1G65160

1 of 13

Yes

Atha\AT1G65165

1 of 13

Yes

Atha\AT1G65170

1 of 13

Yes

Atha\AT5G02660

1 of 13

Yes

Saccharomyces cerevisiae (Brewer's yeast) (0)

Schizosaccharomyces pombe (Fission yeast) (0)

Escherichia coli (enterobacterium) (0)

Other Organism Orthologs (via OrthoDB)

Data provided directly from OrthoDB:ec. Refer to their site for version information.

Paralogs

Downloads

Download All DIOPT Paralogs

Paralogs (via DIOPT v9.1)

Gene Symbol

Score

Source

Alignment

Drosophila melanogaster (Fruit fly) (0)

Human Disease Associations

FlyBase Human Disease Model Reports

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Allele

Disease

Evidence

References

Potential Models Based on Orthology ( 0 )

Human Ortholog

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Allele

Disease

Interaction

References

Disease Associations of Human Orthologs (via DIOPT v9.1 and OMIM)

Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.

Homo sapiens (Human)

Gene name

Score

OMIM

OMIM Phenotype

DO term

Complementation?

Transgene?

USP54; ubiquitin specific peptidase 54

6 of 14

USP53; ubiquitin specific peptidase 53

5 of 14

617431

CHOLESTASIS, PROGRESSIVE FAMILIAL INTRAHEPATIC, 7, WITH OR WITHOUT HEARING LOSS; PFIC7

Functional Complementation Data

Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.

Interactions

Summary of Physical Interactions

esyN Network Diagram

Show neighbor-neighbor interactions:

Off

Show/hide secondary interactors
(data from AllianceMine provided by esyN)

Select Layout:

Force Directed

Circle

Concentric

Legend:

Protein

RNA

Selected Interactor(s)

Other Interaction Browsers

View in FlyBase Interactions Browser View in MIST tool (external link)

Please see the Physical Interaction reports below for full details

protein-protein

Physical Interaction

Assay

References

ec - Pp1-13C

two hybrid

(Bennett et al., 2006)

ec - Pp1-87B

two hybrid

(Bennett et al., 2006)

ec - Pp1α-96A

two hybrid

(Bennett et al., 2006)

ec - flw

two hybrid

(Bennett et al., 2006)

Summary of Genetic Interactions

esyN Network Diagram

Show/hide secondary interactors
(data from AllianceMine provided by esyN)

esyN Network Key:

Suppression

Enhancement

Other Interaction Browsers

View in FlyBase Interactions Browser View in MIST tool (external link)

Please look at the allele data for full details of the genetic interactions

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

suppressible

bsk

(Montrasio et al., 2007)

suppressible

nmo

(Montrasio et al., 2007)

suppressible

(Montrasio et al., 2007)

suppressible

shg

(Montrasio et al., 2007)

suppressible

spi

(Montrasio et al., 2007)

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

External Data

Linkouts

DroID - A comprehensive database of gene and protein interactions.

FBgn0000542

MIST (protein-protein) - An integrated Molecular Interaction Database

31339

Pathways

Signaling Pathways (FlyBase)

Metabolic Pathways

External Data

Linkouts

Genomic Location and Detailed Mapping Data

Chromosome (arm)

Recombination map

1-5

Cytogenetic map

3F2-3F3

Sequence location

X:3,811,698..3,857,621 [+]

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

3F2-3F3

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

Experimentally Determined Recombination Data

Location

1-5

(FlyBase, 2016)

1-4.6

(Comeron et al., 2012)

1-5.5

(Lawlor, 1980, Fraser, 1942)

Left of (cM)

Right of (cM)

(Salz and Kiger, 1984)

Notes

Stocks and Reagents

Stocks (51)

Aberrations including deletions of this gene Aberrations including duplications of this gene

Bloomington

ec¹

ec¹ dx¹

17218

w¹¹¹⁸ P{EP}ec^EP1343

15244

y¹ P{SUPor-P}ec^KG10228

Kyoto

101088

ec¹

105689

ec¹

102042

sc¹ ec¹

105691

ec¹ dx¹

101030

sc¹ z¹ ec¹

101176

sc¹ w^bl ec¹

VDRC

v330077

P{VSH330077}attP40

v106671

P{KK101112}VIE-260B

More stocks available...

Genomic Clones (27)

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones (49)

Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA clones, fully sequenced

BDGP DGC clones

Other clones

Drosophila Genomics Resource Center cDNA clones

For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

FBgn0000542

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

RNAi and Array Information

Linkouts

DRSC - Results frm RNAi screens

FBgn0000542

Antibody Information

Laboratory Generated Antibodies

Commercially Available Antibodies

Cell Line Information

Publicly Available Cell Lines

Other Stable Cell Lines

Other Comments

rst expression and sorting of interommatidial cells are not affected by ec mutations.

(Reiter et al., 1996)

Individuals homozygous for Bpt¹ and ec exhibit no Bpt¹ phenotype. A low frequency of individuals exhibit the lethal pharate adult phenotype.

(Duus et al., 1992)

A screen for rough eye mutants identifies ec, ec is required for normal elimination of surplus cells from the retinal epithelium. Cell death eliminates 2 or 3 cells per ommatidium 35 and 50 hours after pupation.

(Wolff and Ready, 1991)

Relationship to Other Genes

Source for database merge of

Source for merge of: ec CG2904

(FlyBase, 1996-)

Additional comments

Source for merge of ec CG2904 was sequence comparison ( date:040503 ).

(FlyBase, 1996-)

Nomenclature History

Source for database identify of

Nomenclature comments

Etymology

Synonyms and Secondary IDs (6)

Reported As

Symbol Synonym

CG2904

(Pai et al., 2023, Páhi et al., 2022, Meadows, 2017.1.11, Zhou et al., 2015, Tsou et al., 2012, Zhang et al., 2012, Foley et al., 2010, Keleman et al., 2009.8.5, Perkins et al., 2009, Copeland et al., 2007, Bennett et al., 2006)

EG:EG0002.3

(Huntley and Golding, 2004, Butler et al., 2003, Benos, 1998.9.11)

(Parra-Peralbo et al., 2021, Bakshi and Joshi, 2020, Xia et al., 2012)

Q1W9Q0

(Clague et al., 2013)

(Páhi et al., 2022, Badmos et al., 2021, Hao et al., 2020, Gene Disruption Project members, 2018-, Transgenic RNAi Project members, 2017-, Lycette et al., 2016, Nagy et al., 2015, Ashwal-Fluss et al., 2014, Sen et al., 2013, Japanese National Institute of Genetics, 2012.5.21, Tsou et al., 2012, Zhang et al., 2012, Popodi et al., 2010-, Venken et al., 2010, Singh et al., 2009, Copeland et al., 2007, Montrasio et al., 2007, Gilfillan et al., 2006)

echinus

(Du et al., 2020)

Name Synonyms

echinus

(Chan et al., 2012, Singh et al., 2009, Singh et al., 2008, Copeland et al., 2007, Montrasio et al., 2007, Bennett et al., 2006, Manak et al., 2006)

Secondary FlyBase IDs

FBgn0025376

Datasets (0)

Study focus (0)

Experimental Role

Project

Project Type

Title

Study result (0)

Result

Result Type

Title

External Crossreferences and Linkouts ( 49 )

Sequence Crossreferences

NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.

31339

GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.

GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.

RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.

UniProt/GCRP - The gene-centric reference proteome (GCRP) provides a 1:1 mapping between genes and UniProt accessions in which a single 'canonical' isoform represents the product(s) of each protein-coding gene.

Q1W9P9

UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information

Other crossreferences

AlphaFold DB - AlphaFold provides open access to protein structure predictions for the human proteome and other key proteins of interest, to accelerate scientific research.

Q1W9P9

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

31339/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0000542

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0000542

FlyMine - An integrated database for Drosophila genomics

FBgn0000542

InterPro - A database of protein families, domains and functional sites

KEGG Genes - Molecular building blocks of life in the genomic space.

dme:Dmel_CG2904

MARRVEL_MODEL - MARRVEL (model organism gene)

31339

Linkouts

Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones

FBgn0000542

DroID - A comprehensive database of gene and protein interactions.

FBgn0000542

DRSC - Results frm RNAi screens

FBgn0000542

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0000542

FlyCyc Genes - Genes from a BioCyc PGDB for Dmel

FBGN0000542

Flygut - An atlas of the Drosophila adult midgut

FBgn0000542

iBeetle-Base - RNAi phenotypes in the red flour beetle (Tribolium castaneum)

TC011087

MIST (protein-protein) - An integrated Molecular Interaction Database

31339

References (114)

The following external sites may use different assemblies or annotations than FlyBase.

-0.43

Report Sections