FB2024_03 , released June 25, 2024
Gene Group - Macromolecular Complex: SWR1 COMPLEX
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General Information
Name
SWR1 COMPLEX
Species
D. melanogaster
Symbol
SWR1
FlyBase ID
FBgg0001790
Date last reviewed
2023-09-28
Number of members
12
Description
Description
In D.mel, the SWR1 complex is an ATP-dependent histone exchanger that incorporates the histone H2A variant, His2Av. (Adapted from FBrf0245697.)
Notes on Group

Different isoforms of the dom Snf2-like ATPase are present in the SWR1 chromatin remodeling complex and the Tip60 histone acetyltransferase complex. Isoform dom-PB is associated with SWR1 and dom-PA with Tip60 (FBrf0245697).

Source Material
The SWR1 COMPLEX Gene Group has been compiled using the following publication(s): Scacchetti et al., 2020 .
Key Gene Ontology (GO) terms
Molecular Function
Biological Process
Cellular Component
Swr1 complex
Related Gene Groups
Members (12)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
Arp6
Actin-related protein 6
Actr13E, Arp4, dArp6
(Scacchetti et al., 2020)
Bap55
Brahma associated protein 55kD
Arp4
(Scacchetti et al., 2020)
Brd8
Bromodomain containing 8
dBrd8
(Scacchetti et al., 2020)
DMAP1
DNA methyltransferase 1 associated protein 1
dDMAP1
(Scacchetti et al., 2020)
dom
domino
DOM-A
(Scacchetti et al., 2020)
Gas41
Gas41
dGas41
(Scacchetti et al., 2020)
Hcf
Host cell factor
dHCF, Hcf1, dHcf1
(Scacchetti et al., 2020)
MRG15
MORF-related gene 15
dMRG15, DmMRG15, l(3)j6A3
(Scacchetti et al., 2020)
MrgBP
MRG/MORF4L binding protein
dMrgBP, dMrgB
(Scacchetti et al., 2020)
pont
pontin
dPontin, RUVBL1, Tip49/Pontin, Tip49
(Scacchetti et al., 2020)
rept
reptin
l(3)06945, dReptin, psg10, Tip48, Tip48/Reptin
(Scacchetti et al., 2020)
YL-1
YL-1
dYL-1
(Scacchetti et al., 2020)
External Data
Equivalent Group(s)
Other resource(s)
Synonyms and Secondary IDs
Synonym(s)
SWR1
DOM-B complex
DOM-B.C
SWR1 COMPLEX
Secondary FlyBase ID(s)
References (2)