Gene Group: GCN5-CONTAINING COMPLEXES

FB2024_03 , released June 25, 2024

FB2024_03 , released June 25, 2024

Gene Group: GCN5-CONTAINING COMPLEXES

General Information

Name

GCN5-CONTAINING COMPLEXES

Species

D. melanogaster

Symbol

GCN5

FlyBase ID

FBgg0001748

Date last reviewed

2021-08-04

Number of members

32

Description

Description

The Gcn5-containing complexes are large distinct multi-protein transcriptional co-activator complexes that contain Gcn5, a conserved histone acetyltransferase (HAT) as one of the catalytic subunits. These complexes possess global histone acetylation activity and locus-specific co-activator functions. (Adapted from FBrf0247978 and FBrf0248705).

Notes on Group

Source Material

The GCN5-CONTAINING COMPLEXES Gene Group has been compiled using the following publication(s): Helmlinger et al., 2021, Torres-Zelada and Weake, 2021, Soffers et al., 2019, Torres-Zelada et al., 2019, Stegeman et al., 2016, Spedale et al., 2012, Suganuma et al., 2012, Weake et al., 2011, Rodriguez-Navarro, 2009, Suganuma et al., 2008, and Weake et al., 2008 .

Key Gene Ontology (GO) terms

Molecular Function

histone acetyltransferase activity

Biological Process

regulation of transcription by RNA polymerase II

Cellular Component

Enzymatic activity

Enzyme name (EC)

histone acetyltransferase (2.3.1.48)

Related Gene Groups

Parent group(s)

CHROMATIN MODIFYING COMPLEXES

Component group(s)

Members (32)

For all members:

GO ribbon stack

	molecular function	biological process	cellular component

Gene Symbol

Gene Name

Also Known As

Source Material for Membership

transcriptional Adaptor 2b

dAda2b

(Helmlinger et al., 2021, Torres-Zelada and Weake, 2021, Soffers et al., 2019)

transcriptional Adaptor 3

dAda3, dik, diskette

(Helmlinger et al., 2021, Torres-Zelada and Weake, 2021, Soffers et al., 2019)

Gcn5 acetyltransferase

dGcn5, Pcaf, dmGCN5, dKAT2, KAT

(Helmlinger et al., 2021, Torres-Zelada and Weake, 2021, Soffers et al., 2019)

SAGA-associated factor 29kDa

dSgf29

(Helmlinger et al., 2021, Torres-Zelada and Weake, 2021, Soffers et al., 2019)

Gene Symbol

Gene Name

Also Known As

Source Material for Membership

transcriptional Adaptor 2a

dAda2a

(Spedale et al., 2012, Suganuma et al., 2012, Suganuma et al., 2008)

transcriptional Adaptor 3

dAda3, dik, diskette

(Spedale et al., 2012, Suganuma et al., 2012, Suganuma et al., 2008)

Ada2a-containing complex component 1

ATAC component 1

(Spedale et al., 2012, Suganuma et al., 2012, Suganuma et al., 2008)

Ada2a-containing complex component 2

KAT14, ATAC complex component 2

(Spedale et al., 2012, Suganuma et al., 2012, Suganuma et al., 2008)

Ada2a-containing complex component 3

(Spedale et al., 2012, Suganuma et al., 2012, Suganuma et al., 2008)

Chromatin accessibility complex 14kD protein

CHRAC14, PolE3, CHRAC, mary

(Spedale et al., 2012, Suganuma et al., 2012, Suganuma et al., 2008)

D12

(Spedale et al., 2012, Suganuma et al., 2012, Suganuma et al., 2008)

Gcn5 acetyltransferase

dGcn5, Pcaf, dmGCN5, dKAT2, KAT

(Spedale et al., 2012, Suganuma et al., 2012, Suganuma et al., 2008)

Host cell factor

dHCF, Hcf1, dHcf1

(Spedale et al., 2012, Suganuma et al., 2012, Suganuma et al., 2008)

Molybdenum cofactor synthesis 2B

Mocs2, dMoaE

(Spedale et al., 2012, Suganuma et al., 2012, Suganuma et al., 2008)

Negative Cofactor 2β

Dr1, BG:DS00929.3, NC2 beta

(Spedale et al., 2012, Suganuma et al., 2012, Suganuma et al., 2008)

SAGA-associated factor 29kDa

dSgf29

(Spedale et al., 2012, Suganuma et al., 2012, Suganuma et al., 2008)

will die slowly

zw8, l(1)zw8, zw-8, EG:BACR25B3.7, l(1)3Ad

(Spedale et al., 2012, Suganuma et al., 2012, Suganuma et al., 2008)

Gene Symbol

Gene Name

Also Known As

Source Material for Membership

transcriptional Adaptor 2b

dAda2b

(Helmlinger et al., 2021, Torres-Zelada and Weake, 2021, Torres-Zelada et al., 2019)

transcriptional Adaptor 3

dAda3, dik, diskette

(Helmlinger et al., 2021, Torres-Zelada and Weake, 2021, Torres-Zelada et al., 2019)

chiffon

BG:DS09218.1, Dbf4, BG:DS09218.2

(Helmlinger et al., 2021, Torres-Zelada and Weake, 2021, Torres-Zelada et al., 2019)

Gcn5 acetyltransferase

dGcn5, Pcaf, dmGCN5, dKAT2, KAT

(Helmlinger et al., 2021, Torres-Zelada and Weake, 2021, Torres-Zelada et al., 2019)

SAGA-associated factor 29kDa

dSgf29

(Helmlinger et al., 2021, Torres-Zelada and Weake, 2021, Torres-Zelada et al., 2019)

Gene Symbol

Gene Name

Also Known As

Source Material for Membership

transcriptional Adaptor 1-1

Ada1

(Spedale et al., 2012, Weake et al., 2011, Rodriguez-Navarro, 2009)

transcriptional Adaptor 1-2

Ada1

(Stegeman et al., 2016, Spedale et al., 2012, Weake et al., 2011, Rodriguez-Navarro, 2009, Weake et al., 2008)

transcriptional Adaptor 2b

dAda2b

(Stegeman et al., 2016, Spedale et al., 2012, Weake et al., 2011, Rodriguez-Navarro, 2009, Weake et al., 2008)

transcriptional Adaptor 3

dAda3, dik, diskette

(Stegeman et al., 2016, Spedale et al., 2012, Weake et al., 2011, Rodriguez-Navarro, 2009)

Ataxin 7

(Stegeman et al., 2016, Spedale et al., 2012, Weake et al., 2011)

enhancer of yellow 2

ENY2, LBC, late boundary complex

(Stegeman et al., 2016, Spedale et al., 2012, Weake et al., 2011, Rodriguez-Navarro, 2009)

Gcn5 acetyltransferase

dGcn5, Pcaf, dmGCN5, dKAT2, KAT

(Stegeman et al., 2016, Spedale et al., 2012, Weake et al., 2011, Rodriguez-Navarro, 2009, Weake et al., 2008)

Nipped-A

Tra1, TRRAP, dTra1, l(2)41Ah, 41Ah

(Stegeman et al., 2016, Spedale et al., 2012, Weake et al., 2011, Rodriguez-Navarro, 2009)

non-stop

l(3)02069

(Stegeman et al., 2016, Spedale et al., 2012, Weake et al., 2011, Rodriguez-Navarro, 2009, Weake et al., 2008)

SAGA factor-like TAF6

(Stegeman et al., 2016, Spedale et al., 2012, Weake et al., 2011)

Splicing factor 3b subunit 3

(Stegeman et al., 2016)

Splicing factor 3b subunit 5

(Stegeman et al., 2016)

SAGA associated factor 11kDa

dSgf11

(Stegeman et al., 2016, Spedale et al., 2012, Weake et al., 2011, Rodriguez-Navarro, 2009, Weake et al., 2008)

SAGA-associated factor 29kDa

dSgf29

(Stegeman et al., 2016, Spedale et al., 2012, Weake et al., 2011, Rodriguez-Navarro, 2009, Weake et al., 2008)

Spt3

dSpt3

(Stegeman et al., 2016, Spedale et al., 2012, Weake et al., 2011, Rodriguez-Navarro, 2009, Weake et al., 2008)

Spt7

dSpt7

(Stegeman et al., 2016, Spedale et al., 2012, Weake et al., 2011, Rodriguez-Navarro, 2009)

Spt20

lincRNA.S5070

(Stegeman et al., 2016, Spedale et al., 2012, Weake et al., 2011)

TBP-associated factor 9

dTAF_II40, e(y)1, dTAF_II42, TAF_II40, TFIID

(Stegeman et al., 2016, Spedale et al., 2012, Weake et al., 2011, Rodriguez-Navarro, 2009)

TBP-associated factor 10b

TFIID, dTAF_II16, TAF_II16

(Stegeman et al., 2016, Spedale et al., 2012, Weake et al., 2011, Rodriguez-Navarro, 2009)

TBP-associated factor 12

TBP-associated factor 30kD subunit α, Taf30α, dTAF_II30α, TFIID, TAF_II30α

(Stegeman et al., 2016, Spedale et al., 2012, Weake et al., 2011, Rodriguez-Navarro, 2009)

will decrease acetylation

(Stegeman et al., 2016, Spedale et al., 2012, Weake et al., 2011, Rodriguez-Navarro, 2009, Weake et al., 2008)

External Data

Equivalent Group(s)

Other resource(s)

Synonyms and Secondary IDs

Synonym(s)

GCN5

GCN5-CONTAINING COMPLEXES

Secondary FlyBase ID(s)

References (12)

Report Sections