Sulfiredoxin is an antioxidant protein with a role in signaling through catalytic reduction of oxidative modifications. For example, it regulates peroxiredoxins through reduction of the conserved cysteine from sulfinic to sulfenic acid, thereby impacting the role of Prx in regulation of downstream transcription factors and kinase signaling pathways. Srx also has a role in the reduction of glutathionylation, a post-translational, oxidative modification that occurs on numerous proteins. (Adapted from PMID:16102934.)
Notes on Group
The SULFIREDOXINS gene group contains only one member.
Source Material
The
SULFIREDOXINS
Gene Group has been compiled using the following publication(s):
McGinnis et al., 2021
.
