FB2024_03 , released June 25, 2024
Gene Group - Macromolecular Complex: POMT1-POMT2 COMPLEX
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General Information
Name
POMT1-POMT2 COMPLEX
Species
D. melanogaster
Symbol
POMT1-2C
FlyBase ID
FBgg0001683
Date last reviewed
2023-08-08
Number of members
2
Description
Description
The POMT1-POMT2 complex is a heterodimeric mannosyltransferase complex that transfers a mannose residue from dolichyl phosphate D-mannose to the oxygen atom of the hydroxyl group of selected serine/threonine residues of the dystroglycan protein. (Adapted from PMID:31285605 and FBrf0244700).
Notes on Group
Source Material
The POMT1-POMT2 COMPLEX Gene Group has been compiled using the following publication(s): Nakamura et al., 2010, Ueyama et al., 2010, and Ichimiya et al., 2004 .
Key Gene Ontology (GO) terms
Molecular Function
dolichyl-phosphate-mannose-protein mannosyltransferase activity
Biological Process
protein O-linked mannosylation
Cellular Component
dolichyl-phosphate-mannose-protein mannosyltransferase complex
Enzymatic activity
Enzyme name (EC)
dolichyl-phosphate-mannose--protein mannosyltransferase (2.4.1.109)
Related Gene Groups
Other related group(s)
PROTEIN O-MANNOSYLTRANSFERASES
Members (2)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
rt
rotated abdomen
dPOMT1, POMT1
(Nakamura et al., 2010, Ueyama et al., 2010, Ichimiya et al., 2004)
tw
twisted
POMT2, EG:34F3.7, dPOMT2, Protein O-mannosyltransferase 2
(Nakamura et al., 2010, Ueyama et al., 2010, Ichimiya et al., 2004)
External Data
Synonyms and Secondary IDs
Synonym(s)
POMT1-2C
PMT1-2C
PROTEIN O-MANNOSYLTRANSFERASE COMPLEX
POMT1-POMT2 COMPLEX
Secondary FlyBase ID(s)
References (4)