FB2024_03 , released June 25, 2024
Gene Group: DNA POLYMERASE IOTA
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General Information
Name
DNA POLYMERASE IOTA
Species
D. melanogaster
Symbol
DNAPOLI
FlyBase ID
FBgg0001214
Date last reviewed
2019-07-25
Number of members
1
Description
Description
DNA polymerase iota is one of several translesion synthesis polymerases that act to promote replication through DNA lesions that would otherwise stall the replicative polymerases. Instead of Watson-Crick pairing, DNA polymerase iota is specialized to promote Hoogsteen base-pairing (Adapted from PMID:30005324.)
Notes on Group
Source Material
The DNA POLYMERASE IOTA Gene Group has been compiled using the following publication(s): Marygold et al., 2020 .
Key Gene Ontology (GO) terms
Molecular Function
DNA-directed DNA polymerase activity
Biological Process
translesion synthesis
Cellular Component
nucleus
Enzymatic activity
Enzyme name (EC)
DNA-directed DNA polymerase (2.7.7.7)
Related Gene Groups
Parent group(s)
DNA POLYMERASES
Members (1)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
PolI
DNA polymerase iota
DNApol-iota, drad30B, DNApol-ι
(Marygold et al., 2020, FlyBase, 2017-)
External Data
Equivalent Group(s)
Other resource(s)
Synonyms and Secondary IDs
Synonym(s)
DNAPOLI
DNA POLYMERASE IOTA
Secondary FlyBase ID(s)
References (3)