DNA polymerase zeta is one of several translesion synthesis polymerases that act to promote replication through DNA lesions that would otherwise stall the replicative polymerases. It is a heterotetramer, in which the catalytic subunit is encoded by DNApol-ζ, and is specialized for the extension step of lesion bypass. (Adapted from PMID:30005324.)
Notes on Group
The products Pol31 and Pol32 are accessory subunits of both DNA POLYMERASE DELTA and DNA POLYMERASE ZETA.
Source Material
The
DNA POLYMERASE ZETA
Gene Group has been compiled using the following publication(s):
Marygold et al., 2020
.