FB2024_03 , released June 25, 2024
Gene Group - Macromolecular Complex: STRIATIN-INTERACTING PHOSPHATASE AND KINASE COMPLEX
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General Information
Name
STRIATIN-INTERACTING PHOSPHATASE AND KINASE COMPLEX
Species
D. melanogaster
Symbol
STRIPAK
FlyBase ID
FBgg0000915
Date last reviewed
2023-08-08
Number of members
9
Description
Description
Striatin interacting phosphatase and kinase (STRIPAK)/STRIPAK-like complexes contain a protein phosphatase type 2A (mts), a striatin (Cka) and other regulatory subunits. Kinases, such as GckIII, are often associated with the complex (FBrf0211636). The STRIPAK complex has a regulatory role in many signaling pathways and cellular processes. (Adapted from FBrf0223805).
Notes on Group

There are many STRIPAK-like complexes; the exact composition of the complex is context-dependent (FBrf0223805).

Source Material
The STRIATIN-INTERACTING PHOSPHATASE AND KINASE COMPLEX Gene Group has been compiled using the following publication(s): Ashton-Beaucage et al., 2014, Hwang and Pallas, 2014, and Ribeiro et al., 2010 .
Key Gene Ontology (GO) terms
Molecular Function
Biological Process
Cellular Component
FAR/SIN/STRIPAK complex
Related Gene Groups
Other related group(s)
Negative Regulators of Hippo Signaling Pathway
Members (9)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
Ccm3
Cerebral cavernous malformation 3
(Ribeiro et al., 2010)
Cka
Connector of kinase to AP-1
l(2)05836, WD-40-family-member
(Ashton-Beaucage et al., 2014, Hwang and Pallas, 2014, Ribeiro et al., 2010)
Fgop2
Fibroblast growth factor receptor 1 oncogene partner 2
(Ashton-Beaucage et al., 2014, Ribeiro et al., 2010)
Mob4
MOB kinase activator 4
Dmob4
(Ashton-Beaucage et al., 2014, Hwang and Pallas, 2014, Ribeiro et al., 2010)
mts
microtubule star
PP2A, PP2A-C, PP2Ac, PP2A catalytic subunit, protein phosphatase 2A
(Hwang and Pallas, 2014, Ribeiro et al., 2010)
Naus
Nausicaa
(Ribeiro et al., 2010)
Pp2A-29B
Protein phosphatase 2A at 29B
PP2A, PP2A-A, PP2A 29B, PR65
(Hwang and Pallas, 2014, Ribeiro et al., 2010)
Slmap
Sarcolemma associated protein
(Ashton-Beaucage et al., 2014, Hwang and Pallas, 2014)
Strip
Striatin interacting protein
(Ashton-Beaucage et al., 2014, Hwang and Pallas, 2014, Ribeiro et al., 2010)
External Data
Synonyms and Secondary IDs
Synonym(s)
STRIPAK
STRIATIN-INTERACTING PHOSPHATASE AND KINASE COMPLEX
STRIPAK complex
SIP complex
Secondary FlyBase ID(s)
References (4)