FB2024_03 , released June 25, 2024
Gene Group - Macromolecular Complex: MITOCHONDRIAL CALCIUM UNIPORTER COMPLEX
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General Information
Name
MITOCHONDRIAL CALCIUM UNIPORTER COMPLEX
Species
D. melanogaster
Symbol
MCUNI
FlyBase ID
FBgg0000725
Date last reviewed
2023-12-01
Number of members
4
Description
Description
The mitochondrial calcium uniporter complex is a Ca[2+]-activated channel that mediates the import of Ca[2+] ions from the cytosol into the mitochondrion. (Adapted from FBrf0233624).
Notes on Group
Source Material
The MITOCHONDRIAL CALCIUM UNIPORTER COMPLEX Gene Group has been compiled using the following publication(s): Tufi et al., 2019 and Tsai et al., 2016 .
Key Gene Ontology (GO) terms
Molecular Function
calcium channel activity
Biological Process
mitochondrial calcium ion transmembrane transport
Cellular Component
uniplex complex
Related Gene Groups
Parent group(s)
MITOCHONDRIAL CALCIUM UNIPORTER COMPLEXES
Members (4)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
EMRE
Essential MCU regulator
(Tufi et al., 2019, Tsai et al., 2016)
MCU
Mitochondrial calcium uniporter
(Tufi et al., 2019, Tsai et al., 2016)
MICU1
Mitochondrial calcium uptake 1
(Tufi et al., 2019, Tsai et al., 2016)
MICU3
Mitochondrial calcium uptake 3
(Tufi et al., 2019)
External Data
Equivalent Group(s)
Other resource(s)

[Transporter Classification Database:The Mg2+/Ca2+ Uniporter (MCU) Family](https://tcdb.org/search/result.php?tc=1.A.77)

Synonyms and Secondary IDs
Synonym(s)
MCUNI
MCU
MITOCHONDRIAL CALCIUM UNIPORTER COMPLEX
Uniplex complex
Secondary FlyBase ID(s)
References (3)