Gene Group: P-TYPE ATPASES

General Information

Name

P-TYPE ATPASES

Species

D. melanogaster

Symbol

P-ATPASE

FlyBase ID

FBgg0000709

Date last reviewed

2017-03-24

Number of members

Description

The P-type ATPases are transmembrane proteins that utilize the hydrolysis of ATP to actively transport charged substrates like cations and phospholipids across membranes. (Adapted from FBrf0155879).

Notes on Group

All members of the P-type ATPase family have a catalytic (or α) subunit that homodimerizes and contains the site for ATP binding and phosphorylation. The Na,K-ATPase (sodium pump) and the H,K-ATPase (proton pump), in particular, have an additional, glycosylated β-subunit (FBrf0155879).

Source Material

The P-TYPE ATPASES Gene Group has been compiled using the following publication(s): Shiomi et al., 2021, Roy et al., 2013, Ma et al., 2012, Sellami et al., 2012, Desai and Lnenicka, 2011, Tanaka et al., 2011, Bahadorani et al., 2010, Baumann et al., 2010, Burke et al., 2008, Lnenicka et al., 2006, Masly et al., 2006, Norgate et al., 2006, Southall et al., 2006, Roos et al., 2005, Southon et al., 2004, Okamura et al., 2003, Cronin et al., 2002, and Magyar and Varadi, 1990 .

Key Gene Ontology (GO) terms

Molecular Function

P-type transmembrane transporter activity

Biological Process

monoatomic ion transport

Cellular Component

membrane

Related Gene Groups

Parent group(s)

ATPASE-COUPLED TRANSLOCASES

Component group(s)

COPPER TRANSPORTING P-ATPASES

NA⁺/K⁺ TRANSPORTING P-ATPASE - ALPHA SUBUNITS

PHOSPHOLIPID TRANSPORTING ATPASES

PLASMA MEMBRANE CALCIUM TRANSPORTING P-ATPASES

SARCO(ENDO)PLASMIC RETICULUM CALCIUM TRANSPORTING P-ATPASES

TYPE V P-ATPASES

Members (14)

For all members:

GO ribbon stack

	molecular function	biological process	cellular component

COPPER TRANSPORTING P-ATPASES

Gene Symbol

Gene Name

Also Known As

Source Material for Membership

ATP7

DmATP7, lincRNA.S9122

(Sellami et al., 2012, Bahadorani et al., 2010, Burke et al., 2008, Norgate et al., 2006, Southon et al., 2004, Okamura et al., 2003)

NA⁺/K⁺ TRANSPORTING P-ATPASE - ALPHA SUBUNITS

Gene Symbol

Gene Name

Also Known As

Source Material for Membership

Atpα

Na pump α subunit

Na,K-ATPase, Na pump alpha subunit, Na⁺,K⁺-ATPase α-subunit, Na⁺K⁺ATPase, Na+/K+-ATPase

(Roy et al., 2013, Baumann et al., 2010, Okamura et al., 2003)

JYalpha

(Masly et al., 2006, Okamura et al., 2003)

PHOSPHOLIPID TRANSPORTING ATPASES

Gene Symbol

Gene Name

Also Known As

Source Material for Membership

ATP8A

ATPase 8A