FB2024_03 , released June 25, 2024
Gene Group - Macromolecular Complex: M6A METHYLTRANSFERASE COMPLEX
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General Information
Name
M6A METHYLTRANSFERASE COMPLEX
Species
D. melanogaster
Symbol
MTC
FlyBase ID
FBgg0000702
Date last reviewed
2023-08-08
Number of members
7
Description
Description
The m6A methyltransferase complex is a nuclear, multi-component enzyme involved in mediating N6-methyladenosine (m6A) modification in mRNAs. This modification modulates mRNA processing and activity. (Adapted from FBrf0234210 and FBrf0234211).
Notes on Group
Source Material
The M6A METHYLTRANSFERASE COMPLEX Gene Group has been compiled using the following publication(s): Bawankar et al., 2021, Wang et al., 2021, Knuckles et al., 2018, Kan et al., 2017, Haussmann et al., 2016, and Lence et al., 2016 .
Key Gene Ontology (GO) terms
Molecular Function
mRNA m(6)A methyltransferase activity
Biological Process
mRNA modification
Cellular Component
RNA N6-methyladenosine methyltransferase complex
Enzymatic activity
Enzyme name (EC)
mRNA m(6)A methyltransferase (2.1.1.348)
Related Gene Groups
Members (7)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
fl(2)d
female lethal d
v(2)k16105, female-lethal(2)d, Female-lethal (2)d
(Kan et al., 2017, Haussmann et al., 2016, Lence et al., 2016)
Flacc
Fl(2)d-associated complex component
xio
(Knuckles et al., 2018)
Hakai
Hakai
(Bawankar et al., 2021, Wang et al., 2021)
Mettl3
Methyltransferase like 3
Ime4, Inducer of meiosis 4
(Kan et al., 2017, Haussmann et al., 2016, Lence et al., 2016)
Mettl14
Methyltransferase like 14
dMettl14
(Kan et al., 2017, Haussmann et al., 2016, Lence et al., 2016)
nito
spenito
dOTT, BcDNA:GH11110, DmSSp
(Kan et al., 2017, Lence et al., 2016)
vir
virilizer
(Kan et al., 2017, Haussmann et al., 2016)
External Data
Synonyms and Secondary IDs
Synonym(s)
MTC
M6A METHYLTRANSFERASE COMPLEX
m6A Methylosome
Secondary FlyBase ID(s)
References (7)