FB2024_04 , released June 25, 2024
Gene Group - Macromolecular Complex: U4-U6-U5 SMALL NUCLEAR RIBONUCLEOPROTEIN PARTICLE
Open Close
General Information
Name
U4-U6-U5 SMALL NUCLEAR RIBONUCLEOPROTEIN PARTICLE
Species
D. melanogaster
Symbol
U4-U6-U5
FlyBase ID
FBgg0000525
Date last reviewed
2016-08-11
Number of members
42
Description
Description
U4/U6.U5 tri-snRNP is assembled from U5 and U4/U6 snRNPs. The complex contains U4 and U6 snRNAs base-paired with each other and U6 snRNA. This complex is recruited to the pre-catalytic splicing intermediate, complex B. (Adapted from PMID:21441581).
Notes on Group
Source Material
The U4-U6-U5 SMALL NUCLEAR RIBONUCLEOPROTEIN PARTICLE Gene Group has been compiled using the following publication(s): Lu and Matera, 2014, Cvitkovic and Jurica, 2013, and Saluz et al., 1988 .
Key Gene Ontology (GO) terms
Molecular Function
Biological Process
mRNA splicing, via spliceosome
Cellular Component
U4/U6 x U5 tri-snRNP complex
Related Gene Groups
Parent group(s)
SPLICEOSOMAL SMALL NUCLEAR RIBONUCLEOPROTEIN PARTICLES
Members (42)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
Brr2
Brr2 U5 snRNP complex subunit
l(3)72Ab
(Cvitkovic and Jurica, 2013)
CG2021
l(3)neo7, l(3)62Be
(Cvitkovic and Jurica, 2013)
CG3436
(Cvitkovic and Jurica, 2013)
CG4849
eEF2
(Cvitkovic and Jurica, 2013)
CG6610
(Cvitkovic and Jurica, 2013)
CG6686
(Cvitkovic and Jurica, 2013)
CG9344
(Cvitkovic and Jurica, 2013)
CG10333
DmPrp28, DmRH19
(Cvitkovic and Jurica, 2013)
CG10418
(Cvitkovic and Jurica, 2013)
CG17266
(Cvitkovic and Jurica, 2013)
CG17768
(Cvitkovic and Jurica, 2013)
Dim1
Dim1
(Cvitkovic and Jurica, 2013)
hoip
hoi-polloi
l(2)FE3
(Cvitkovic and Jurica, 2013)
holn1
hole-in-one
(Cvitkovic and Jurica, 2013)
LSm3
Like Sm 3
(Cvitkovic and Jurica, 2013)
LSm7
Like Sm 7
(Cvitkovic and Jurica, 2013)
Prp3
Precursor RNA processing 3
(Cvitkovic and Jurica, 2013)
Prp6
pre-mRNA processing factor 6
(Cvitkovic and Jurica, 2013)
Prp8
pre-mRNA processing factor 8
(Cvitkovic and Jurica, 2013)
Prp31
Pre-mRNA processing factor 31
(Cvitkovic and Jurica, 2013)
SmB
Small ribonucleoprotein particle protein SmB
Sm B, Small ribonucleoprotein particle protein B
(Cvitkovic and Jurica, 2013)
SmD1
Small ribonucleoprotein particle protein SmD1
snRNP69D
(Cvitkovic and Jurica, 2013)
SmD2
Small ribonucleoprotein particle protein SmD2
snRNP2
(Cvitkovic and Jurica, 2013)
SmD3
Small ribonucleoprotein particle protein SmD3
guf, l(2)90/37, gut feeling
(Cvitkovic and Jurica, 2013)
SmE
Small ribonucleoprotein particle protein SmE
snRNPE
(Cvitkovic and Jurica, 2013)
SmF
Small ribonucleoprotein particle protein SmF
DebB, Deb-B
(Cvitkovic and Jurica, 2013)
snRNA:U4:25F
small nuclear RNA U4 at 25F
U4, U4 snRNA, dU4, U4-25F, snRNA, U425F
(Lu and Matera, 2014, Cvitkovic and Jurica, 2013)
snRNA:U4:38AB
small nuclear RNA U4 at 38AB
U4, U4 snRNA, U4-1, U4:38AB, dU4
(Lu and Matera, 2014, Saluz et al., 1988)
snRNA:U4:39B
small nuclear RNA U4 at 39B
U4, U4 snRNA, U4-2, U4:39B, U4-39B
(Lu and Matera, 2014, Saluz et al., 1988)
snRNA:U5:14B
small nuclear RNA U5 at 14B
U5, U5 snRNA, U5:14B, dU5, snRNA:U5
(Lu and Matera, 2014, Saluz et al., 1988)
snRNA:U5:23D
small nuclear RNA U5 at 23D
U5, U5 snRNA, U5:23D, dU5, snRNA:U5
(Lu and Matera, 2014, Saluz et al., 1988)
snRNA:U5:34A
small nuclear RNA U5 at 34A
U5, U5:34A, U5 snRNA, snRNA:U5, dU5
(Lu and Matera, 2014, Cvitkovic and Jurica, 2013, Saluz et al., 1988)
snRNA:U5:35D
small nuclear RNA U5 at 35D
U5, U5 snRNA, dU5, U5:35D
(Lu and Matera, 2014, Saluz et al., 1988)
snRNA:U5:38ABa
small nuclear RNA U5 at 38AB a
U5, U5 snRNA, U5:38ABa, dU5, snRNA:U5
(Lu and Matera, 2014)
snRNA:U5:38ABb
small nuclear RNA U5 at 38AB b
U5, U5 snRNA, snRNA:U5, U5:38ABb, dU5
(Lu and Matera, 2014)
snRNA:U5:63BC
small nuclear RNA U5 at 63BC
U5, U5:63BC, U5 snRNA, snRNA:U5, dU5
(Lu and Matera, 2014, Saluz et al., 1988)
snRNA:U6:96Aa
small nuclear RNA U6 at 96A a
U6, U6 snRNA, U6-1, snRNA-b, U6 RNA
(Saluz et al., 1988)
snRNA:U6:96Ab
small nuclear RNA U6 at 96A b
U6, U6-2, U6:96Ab, U6 snRNA, U6 RNA
(Cvitkovic and Jurica, 2013, Saluz et al., 1988)
snRNA:U6:96Ac
small nuclear RNA U6 at 96A c
U6, U6 snRNA, U6 RNA, snRNA-b, snRNA:U6
(Saluz et al., 1988)
SNRPG
Small nuclear ribonucleoprotein G
SmG, snRNPG
(Cvitkovic and Jurica, 2013)
U4-U6-60K
U4-U6 small nuclear riboprotein factor 60K
(Cvitkovic and Jurica, 2013)
Usp39
Ubiquitin specific protease 39
(Cvitkovic and Jurica, 2013)
External Data
Equivalent Group(s)
Other resource(s)
Synonyms and Secondary IDs
Synonym(s)
U4-U6-U5
Tri-snRNP
U4-U6-U5 SMALL NUCLEAR RIBONUCLEOPROTEIN PARTICLE
U4/U6.U5 tri-snRNP
Secondary FlyBase ID(s)
References (4)