FB2024_02 , released April 23, 2024
Gene Group: HEAT SHOCK PROTEINS
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General Information
Name
HEAT SHOCK PROTEINS
Species
D. melanogaster
Symbol
HSP
FlyBase ID
FBgg0000501
Date last reviewed
2016-04-21
Number of members
87
Description
Description
Heat Shock Proteins (HSP) are molecular chaperones found in all organisms. HSPs assist in protein folding and prevent accumulation of damaged, misfolded proteins. They are subdivided in distinct families based on their molecular weight and sequence homology. (Adapted from FBrf0228040 and FBrf0231212).
Notes on Group
Source Material
The HEAT SHOCK PROTEINS Gene Group has been compiled using the following publication(s): Kaneko, 2022, Jagla et al., 2018, Raut et al., 2017, Li et al., 2016, Morrow et al., 2016, Vos et al., 2016, Pantzartzi et al., 2013, Ratheesh et al., 2012, Monzo et al., 2010, Takahashi et al., 2010, Li et al., 2009, Arya et al., 2007, Chen et al., 2006, Morrow et al., 2006, Sarkar and Lakhotia, 2005, Nikolaidis and Nei, 2004, Michaud et al., 2002, and Easton et al., 2000 .
Key Gene Ontology (GO) terms
Molecular Function
Biological Process
Cellular Component
Related Gene Groups
Parent group(s)
CHAPERONES AND CO-CHAPERONES
Component group(s)
ATYPICAL HEAT SHOCK PROTEIN 70 CHAPERONES
HEAT SHOCK PROTEIN 10 CHAPERONINS
HEAT SHOCK PROTEIN 40/DNAJ CO-CHAPERONES
HEAT SHOCK PROTEIN 60 CHAPERONINS
HEAT SHOCK PROTEIN 70 CHAPERONES
HEAT SHOCK PROTEIN 90 CHAPERONES
HEAT SHOCK PROTEIN 100 CHAPERONES
SMALL HEAT SHOCK PROTEINS
Other related group(s)
CANOPY CO-CHAPERONES
Members (87)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
ATYPICAL HEAT SHOCK PROTEIN 70 CHAPERONES
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
Grp170
Grp170 co-chaperone
EG:25E8.1
(Ratheesh et al., 2012, Easton et al., 2000)
Hsp110
Heat shock protein 110
Hsc70Cb, dHsp110, Hsc70, l(3)70Ca, l(3)00082
(Ratheesh et al., 2012, Nikolaidis and Nei, 2004, Easton et al., 2000)
CHAPERONIN CONTAINING TCP-1 COMPLEX
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
CCT1
Chaperonin containing TCP1 subunit 1
T-cp1, Tcp1-like, Tcp1, T-cpl, TCP1α
(Monzo et al., 2010)
CCT2
Chaperonin containing TCP1 subunit 2
(Monzo et al., 2010)
CCT3
Chaperonin containing TCP1 subunit 3
Cctgamma, Cctγ, Y, Cctg, vine
(Monzo et al., 2010)
CCT4
Chaperonin containing TCP1 subunit 4
(Monzo et al., 2010)
CCT5
Chaperonin containing TCP1 subunit 5
l(2)06444, T-complex Chaperonin 5
(Monzo et al., 2010)
CCT6
Chaperonin containing TCP1 subunit 6
Tcp-1zeta, l(1)G0057, Tcp-1ζ, lethal (1) G0022, T-cp1ζ
(Monzo et al., 2010)
CCT7
Chaperonin containing TCP1 subunit 7
Tcp-1eta, Tcp-1η
(Monzo et al., 2010)
CCT8
Chaperonin containing TCP1 subunit 8
(Monzo et al., 2010)
HEAT SHOCK PROTEIN 10 CHAPERONINS
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
CG9920
(Ratheesh et al., 2012)
CG11267
Hsp10
(Ratheesh et al., 2012)
HEAT SHOCK PROTEIN 40/DNAJ CO-CHAPERONES
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
aux
auxilin
auxillin, dAux
(Ratheesh et al., 2012)
blp
black pearl
l(3)01618
(Ratheesh et al., 2012)
CG1409
(Ratheesh et al., 2012)
CG2790
(Ratheesh et al., 2012)
CG2887
(Ratheesh et al., 2012)
CG3061
(Ratheesh et al., 2012)
CG5001
(Ratheesh et al., 2012)
CG5504
l(2)tid, lethal (2) tumorous imaginal discs, DnaJ, lethal(2) tumorous imaginal discs, lethal(2)tumorous imaginal discs
(Ratheesh et al., 2012)
CG6693
(Ratheesh et al., 2012)
CG7130
(Ratheesh et al., 2012)
CG7133
(Ratheesh et al., 2012)
CG7387
(Ratheesh et al., 2012)
CG7394
(Ratheesh et al., 2012)
CG7556
(Ratheesh et al., 2012)
CG7872
(Ratheesh et al., 2012)
CG8476
(Ratheesh et al., 2012)
CG8531
(Ratheesh et al., 2012)
CG10375
(Ratheesh et al., 2012)
CG10565
(Ratheesh et al., 2012)
CG11035
(Ratheesh et al., 2012)
CG12020
(Ratheesh et al., 2012)
CG14650
(Ratheesh et al., 2012)
CG17187
(Ratheesh et al., 2012)
CG30156
(Ratheesh et al., 2012)
CG32640
(Ratheesh et al., 2012)
CG32641
(Ratheesh et al., 2012)
CG32727
anon-SAGE:Wang-041
(Ratheesh et al., 2012)
CG43322
(Ratheesh et al., 2012)
Csp
Cysteine string protein
cystein string protein, l(3)03988, Dcsp, ab49
(Ratheesh et al., 2012)
DnaJ-1
DnaJ-like-1
Hsp40, dHDJ1, droj1, dHSP40, DNAJ1
(Li et al., 2016, Ratheesh et al., 2012)
DnaJ-60
DnaJ-like-60
DnaJ60
(Ratheesh et al., 2012)
DnaJ-H
DnaJ homolog
(Ratheesh et al., 2012)
Droj2
DnaJ-like-2
(Li et al., 2016, Ratheesh et al., 2012)
Hsc20
Heat shock protein cognate 20
l(3)72Do
(Ratheesh et al., 2012)
jdp
jdp
dJDP
(Ratheesh et al., 2012)
l(3)80Fg
lethal (3) 80Fg
l4A, l(3)Lh4A
(Ratheesh et al., 2012)
mrj
mrj
dMRJ
(Li et al., 2016, Ratheesh et al., 2012)
P58IPK
P58IPK
(Ratheesh et al., 2012)
Rme-8
Receptor mediated endocytosis 8
l(2)45Ba
(Ratheesh et al., 2012)
Sec63
Secretory 63
(Ratheesh et al., 2012)
shv
shriveled
(Ratheesh et al., 2012)
Tpr2
Tetratricopeptide repeat protein 2
dTPR2, Trp2
(Ratheesh et al., 2012)
wus
wurst
(Ratheesh et al., 2012)
HEAT SHOCK PROTEIN 60 CHAPERONINS - GROUP I
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
Hsp60A
Heat shock protein 60A
Hsp60, l(1)BP5, heat shock protein 60, Hsp 60, 12
(Morrow et al., 2016, Arya et al., 2007, Sarkar and Lakhotia, 2005)
Hsp60B
Heat shock protein 60B
ms(2)21D, Hsp64, Heat shock protein 60 related
(Morrow et al., 2016, Arya et al., 2007, Sarkar and Lakhotia, 2005)
Hsp60C
Heat shock protein 60C
Hsp64
(Morrow et al., 2016, Arya et al., 2007, Sarkar and Lakhotia, 2005)
Hsp60D
Heat shock protein 60D
(Morrow et al., 2016, Arya et al., 2007, Sarkar and Lakhotia, 2005)
HEAT SHOCK PROTEIN 70 CHAPERONES
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
CG7182
(FlyBase, 2017-)
Hsc70-1
Heat shock protein 70 cognate 1
Hsc70, Heat shock protein cognate 1, Hsc1
(Kaneko, 2022, Ratheesh et al., 2012)
Hsc70-2
Heat shock protein 70 cognate 2
Hsc70, Heat shock protein cognate 2, hsc2, Hsc70.2
(Kaneko, 2022, Ratheesh et al., 2012, Nikolaidis and Nei, 2004)
Hsc70-3
Heat shock protein 70 cognate 3
BiP, Hsc3, Hsc70, Grp78, Hsc-70-3
(Kaneko, 2022, Ratheesh et al., 2012, Nikolaidis and Nei, 2004)
Hsc70-4
Heat shock protein 70 cognate 4
Hsc4, Hsc70, Heat shock protein cognate 4, BAP74, scattered
(Kaneko, 2022, Ratheesh et al., 2012, Nikolaidis and Nei, 2004)
Hsc70-5
Heat shock protein 70 cognate 5
Hsc5, Hsc70, Heat shock protein cognate 5, l(2)k04907, Heat shock 70 kDa protein cognate 5
(Kaneko, 2022, Ratheesh et al., 2012, Nikolaidis and Nei, 2004)
Hsp68
Heat shock protein 68
68
(Kaneko, 2022, Ratheesh et al., 2012)
Hsp70Aa
Heat shock protein 70 Aa
hsp70, Hsp70A, hsp-70, hsp70 87A, heat-shock protein 70
(Kaneko, 2022, Nikolaidis and Nei, 2004)
Hsp70Ab
Heat shock protein 70 Ab
hsp70, Hsp70A, hsp-70, heat-shock protein 70
(Kaneko, 2022, Ratheesh et al., 2012, Nikolaidis and Nei, 2004)
Hsp70Ba
Heat shock protein 70 Ba
hsp70, Hsp70B, hsp-70, hsp70 87C, heat-shock protein 70
(Kaneko, 2022, Ratheesh et al., 2012, Takahashi et al., 2010, Nikolaidis and Nei, 2004)
Hsp70Bb
Heat shock protein 70 Bb
hsp70, Hsp70B, hsp-70, heat-shock protein 70, Hsp70Bc
(Kaneko, 2022, Ratheesh et al., 2012, Takahashi et al., 2010, Nikolaidis and Nei, 2004)
Hsp70Bbb
Heat shock protein 70 Bbb
Hsp70, heat-shock protein 70, hsp70B
(Kaneko, 2022, Ratheesh et al., 2012, Takahashi et al., 2010)
Hsp70Bc
Heat shock protein 70 Bc
hsp70, Hsp70B, heat-shock protein 70, hsp-70
(Kaneko, 2022, Takahashi et al., 2010, Nikolaidis and Nei, 2004)
HEAT SHOCK PROTEIN 90 CHAPERONES
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
Gp93
Glycoprotein 93
Hsp90, dGRP94
(Pantzartzi et al., 2013, Chen et al., 2006)
Hsp83
Heat shock protein 83
Hsp90, hsp82, l(3)j5C2, E(sev)3A, E(sina)2
(Pantzartzi et al., 2013, Chen et al., 2006)
Trap1
Trap1
(Pantzartzi et al., 2013, Chen et al., 2006)
HEAT SHOCK PROTEIN 100 CHAPERONES
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
ClpX
Caseinolytic protease chaperone subunit
(Raut et al., 2017)
SMALL HEAT SHOCK PROTEINS
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
CG4461
Hsp20
(Jagla et al., 2018, Vos et al., 2016, Li et al., 2009, Michaud et al., 2002)
CG7409
(Jagla et al., 2018, Vos et al., 2016, Li et al., 2009, Michaud et al., 2002)
CG13133
(Jagla et al., 2018, Vos et al., 2016, Li et al., 2009, Michaud et al., 2002)
CG14207
HspB8
(Jagla et al., 2018, Vos et al., 2016, Li et al., 2009, Michaud et al., 2002)
Hsp22
Heat shock protein 22
DmHsp22, dHsp22
(Jagla et al., 2018, Vos et al., 2016, Takahashi et al., 2010, Li et al., 2009, Morrow et al., 2006, Michaud et al., 2002)
Hsp23
Heat shock protein 23
23, DmHsp23
(Jagla et al., 2018, Vos et al., 2016, Li et al., 2009, Morrow et al., 2006, Michaud et al., 2002)
Hsp26
Heat shock protein 26
26, DmHsp26, Hsp 26
(Jagla et al., 2018, Vos et al., 2016, Takahashi et al., 2010, Li et al., 2009, Morrow et al., 2006, Michaud et al., 2002)
Hsp27
Heat shock protein 27
Hsp28, Dhsp27, DmHsp27, Hsp 27
(Jagla et al., 2018, Vos et al., 2016, Takahashi et al., 2010, Li et al., 2009, Morrow et al., 2006, Michaud et al., 2002)
Hsp67Ba
Heat shock gene 67Ba
gene 1, gene1
(Jagla et al., 2018, Vos et al., 2016, Takahashi et al., 2010, Li et al., 2009, Michaud et al., 2002)
Hsp67Bc
Heat shock gene 67Bc
gene 3
(Jagla et al., 2018, Vos et al., 2016, Takahashi et al., 2010, Li et al., 2009, Michaud et al., 2002)
l(2)efl
lethal (2) essential for life
CryAB, dCryAB
(Jagla et al., 2018, Vos et al., 2016, Li et al., 2009, Michaud et al., 2002)
External Data
Equivalent Group(s)
Other resource(s)

[Heat shock protein information resource](http://pdslab.biochem.iisc.ernet.in/hspir/index.php)

Synonyms and Secondary IDs
Synonym(s)
HSP
HEAT SHOCK PROTEINS
Secondary FlyBase ID(s)
References (20)