FB2024_03 , released June 25, 2024
Gene Group: GEMINS
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General Information
Name
GEMINS
Species
D. melanogaster
Symbol
GEM
FlyBase ID
FBgg0000470
Date last reviewed
2016-03-15
Number of members
6
Description
Description
Gemin proteins are found in the nuclear Gemini of coiled bodies or in U bodies. Gemins interact notably with Smn to form the SMN complex. (Adapted from FBrf0223758).
Notes on Group

Lanfranco et al. (FBrf0237151) suggest that Hez, Sbat and Vlet are orthologous to metazoan Gemin6, Gemin7 and Gemin8, respectively, and are components of the SMN complex. However, the data of Matera et al. (FBrf0241402) argue against this. The composition of the GEMINS group reflects conclusions of Matera et al.

Source Material
The GEMINS Gene Group has been compiled using the following publication(s): Matera et al., 2019, Lanfranco et al., 2017, Borg et al., 2015, Borg and Cauchi, 2013, Cauchi et al., 2010, and Shpargel et al., 2009 .
Key Gene Ontology (GO) terms
Molecular Function
Biological Process
spliceosomal snRNP assembly
Cellular Component
cytoplasmic U snRNP body
Related Gene Groups
Protein Complex group(s)
SURVIVAL MOTOR NEURON COMPLEX - GEM4A VARIANT
Members (6)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
Gem2
Gemin 2
(Matera et al., 2019, Borg et al., 2015, Borg and Cauchi, 2013, Cauchi et al., 2010, Shpargel et al., 2009)
Gem3
Gemin 3
l(3)rL562, Dhh1, dGem3
(Matera et al., 2019, Borg et al., 2015, Borg and Cauchi, 2013, Cauchi et al., 2010, Shpargel et al., 2009)
Gem4b
Gemin 4b
(Matera et al., 2019)
Gem4c
Gemin 4c
(Matera et al., 2019)
Glos
Gaulos
Gem4a, Gemin4
(Matera et al., 2019)
rig
rigor mortis
Gemin5, Gem5, l(2)05056, anon-SAGE:Wang-132
(Matera et al., 2019, Borg et al., 2015, Borg and Cauchi, 2013, Cauchi et al., 2010, Shpargel et al., 2009)
External Data
Equivalent Group(s)
Other resource(s)
Synonyms and Secondary IDs
Synonym(s)
GEM
GEMINS
Gem nuclear organelle associated proteins
Secondary FlyBase ID(s)
References (7)