FB2024_03 , released June 25, 2024
Gene Group - Macromolecular Complex: BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEX-1
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General Information
Name
BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEX-1
Species
D. melanogaster
Symbol
BLOC1
FlyBase ID
FBgg0000185
Date last reviewed
Number of members
8
Description
Description
The BLOC (biogenesis of lysosome-related organelles complex) complexes are required for the biogenesis of specialized organelles of the endosomal-lysosomal system. In mammalian cells, BLOC-1 localizes to early endosomes and facilitates protein trafficking to melanosomes in melanocytes. In D.mel, BLOC-1 has been shown to be involved in pigment granule biogenesis. (Adapted from FBrf0192474).
Notes on Group
Source Material
The BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEX-1 Gene Group has been compiled using the following publication(s): Cheli and Dell'Angelica, 2010, Cheli et al., 2010, Rodriguez-Fernandez and Dell'angelica, 2009, and Falcon-Perez et al., 2007 .
Key Gene Ontology (GO) terms
Molecular Function
Biological Process
eye pigment granule organization
Cellular Component
BLOC-1 complex
Related Gene Groups
Parent group(s)
BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEXES
Protein Complex group(s)
BLOC1-RELATED COMPLEX
Members (8)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
Blos1
Biogenesis of lysosome-related organelles complex 1, subunit 1
(Cheli and Dell'Angelica, 2010, Cheli et al., 2010, Rodriguez-Fernandez and Dell'angelica, 2009, Falcon-Perez et al., 2007)
Blos2
Biogenesis of lysosome-related organelles complex 1, subunit 2
(Cheli and Dell'Angelica, 2010, Cheli et al., 2010, Rodriguez-Fernandez and Dell'angelica, 2009, Falcon-Perez et al., 2007)
Blos3
Biogenesis of lysosome-related organelles complex 1, subunit 3
(Cheli and Dell'Angelica, 2010, Cheli et al., 2010)
Blos4
Biogenesis of lysosome-related organelles complex 1, subunit 4
(Cheli and Dell'Angelica, 2010, Cheli et al., 2010, Rodriguez-Fernandez and Dell'angelica, 2009, Falcon-Perez et al., 2007)
Dysb
Dysbindin
Ddysb
(Cheli and Dell'Angelica, 2010, Cheli et al., 2010, Rodriguez-Fernandez and Dell'angelica, 2009, Falcon-Perez et al., 2007)
Muted
Muted
(Cheli and Dell'Angelica, 2010, Cheli et al., 2010, Rodriguez-Fernandez and Dell'angelica, 2009, Falcon-Perez et al., 2007)
Pldn
Pallidin
(Cheli and Dell'Angelica, 2010, Cheli et al., 2010, Rodriguez-Fernandez and Dell'angelica, 2009, Falcon-Perez et al., 2007)
Snapin
SNAP associated protein
(Cheli and Dell'Angelica, 2010, Cheli et al., 2010, Rodriguez-Fernandez and Dell'angelica, 2009, Falcon-Perez et al., 2007)
External Data
Synonyms and Secondary IDs
Synonym(s)
BLOC1
BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEX-1
Biogenesis of lysosomal organelles complex-1
BLOC-1
Secondary FlyBase ID(s)
References (5)