FB2024_03 , released June 25, 2024
Chemical: tioguanine
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General Information
Name
tioguanine
FlyBase ID
FBch0002113
ChEBI Name
tioguanine
ChEBI ID
PubChem Name
Thioguanine
PubChem ID
2723601 (PubChem link: Thioguanine)
Chemical Structure
Chemical structure of tioguanine
tioguanine
InChIKey

WYWHKKSPHMUBEB-UHFFFAOYSA-N

Definition (ChEBI)

A 2-aminopurine that is the 6-thiono derivative of 2-amino-1,9-dihydro-6H-purine. Incorporates into DNA and inhibits synthesis. Used in the treatment of leukaemia. ChEBI: Tioguanine is a 2-aminopurine that is the 6-thiono derivative of 2-amino-1,9-dihydro-6H-purine. Incorporates into DNA and inhibits synthesis. Used in the treatment of leukaemia. It has a role as an antineoplastic agent, an antimetabolite and an anticoronaviral agent.

Roles Classification (ChEBI)
Comment
Synonyms and Secondary IDs (27)
Synonyms
154-42-7
2-Amino 6MP
2-Amino-1,7-dihydro-6H-purine-6-thione
2-Amino-6-mercaptopurine
2-Amino-6-merkaptopurin
2-Amino-6-purinethiol
2-Aminopurin-6-thiol
2-Aminopurine-6(1H)-thione
2-Aminopurine-6-thiol
2-amino-1,9-dihydropurine-6-thione
6-Mercapto-2-aminopurine
6-Mercaptoguanine
6-thioguanine
PubChem:2723601
Tioguanine
thioguanine
tioguanina
tioguaninum
Secondary FlyBase IDs
    References (3)