FB2024_03 , released June 25, 2024
Chemical: aphidicolin
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General Information
Name
aphidicolin
FlyBase ID
FBch0001636
ChEBI Name
aphidicolin
ChEBI ID
CHEBI:2766
PubChem Name
Aphidicolin
PubChem ID
457964 (PubChem link: Aphidicolin)
Chemical Structure
Chemical structure of aphidicolin
aphidicolin
InChIKey

NOFOAYPPHIUXJR-APNQCZIXSA-N

Definition (ChEBI)

A tetracyclic diterpenoid that has an tetradecahydro-8,11a-methanocyclohepta[a]naphthalene skeleton with two hydroxymethyl substituents at positions 4 and 9, two methyl substituents at positions 4 and 11b and two hydroxy substituents at positions 3 and 9. An antibiotic with antiviral and antimitotical properties. Aphidicolin is a reversible inhibitor of eukaryotic nuclear DNA replication.

Roles Classification (ChEBI)
Comment
Synonyms and Secondary IDs (22)
Synonyms
(+)-Aphidicolin
(PubChem, 2019-)
(+)-aphidicolin
(PubChem, 2019-)
(+/-)-Aphidicolin
(PubChem, 2019-)
(+/-)-aphidicolin
(PubChem, 2019-)
(3R,4R,4aR,6aS,8R,9R,11aS,11bS)-4,9-bis(hydroxymethyl)-4,11b-dimethyltetradecahydro-8,11a-methanocyclohepta[a]naphthalene-3,9-diol
(PubChem, 2019-)
(3alpha,4alpha,5alpha,17alpha)-3,17-dihydroxy-4-methyl-9,15-cyclo-C,18-dinor-14,15-secoandrostane-4,17-dimethanol
(ChEBI, 2019-)
(3r,4r,4ar,6as,8r,9r,11as,11bs)-4,9-bis(hydroxymethyl)-4,11b-dimethyltetradecahydro-8,11a-methanocyclohepta[a]naphthalene-3,9-diol
(PubChem, 2019-)
38966-21-1
(PubChem, 2019-)
6B3F8QW8TU
(PubChem, 2019-)
6b3f8qw8tu
(PubChem, 2019-)
Aphidicolin, (+/-)-
(PubChem, 2019-)
ICI 69653
(PubChem, 2019-)
NSC-234714
(PubChem, 2019-)
NSC234714
(PubChem, 2019-)
PubChem:457964
(PubChem, 2019-)
aphidicolin
(ChEBI, 2019-, PubChem, 2019-, Krause et al., 2001)
aphidicolin, (+/-)-
(PubChem, 2019-)
aphidocolin
(ChEBI, 2019-)
ici 69653
(PubChem, 2019-)
nsc-234714
(PubChem, 2019-)
nsc234714
(PubChem, 2019-)
pubchem:457964
(PubChem, 2019-)
Secondary FlyBase IDs
    References (3)