FB2024_03 , released June 25, 2024
Allele: Dmel\CG5674btv-4
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General Information
Symbol
Dmel\CG5674btv-4
Species
D. melanogaster
Name
FlyBase ID
FBal0397109
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Caused by aberration
    Cytology
    Description

    3196bp deletion (plus insertion of a single G nucleotide). The deletion extends from 1377bp left of the P{GT1}btvBG01771 insertion site rightwards into the intron between exons 11-12 of btv. The deletion thus deletes two exons from btv and introduces a frameshift. In addition, the lesion is predicted to remove 60 C-terminal amino acids from CG5674, replacing them through frameshifting with 24 unrelated amino acids before termination. The mutation was generated in heterozygotes containing both the P{GT1}btvBG01771 and P{SUPor-P}KG02815 insertions, in the presence of P-element transposase (the mechanism of deletion cannot be verified, but the most likely event is simple imprecise excision of the P{GT1}btvBG01771 element without flanking exchange).

    Mutations Mapped to the Genome
    Curation Data
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    Variant Molecular Consequences
    Associated Sequence Data
    DNA sequence
    Protein sequence
     
    Expression Data
    Reporter Expression
    Additional Information
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    Marker for
    Reflects expression of
    Reporter construct used in assay
    Human Disease Associations
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Disease
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    Modifiers Based on Experimental Evidence ( 0 )
    Disease
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    Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
     
    Disease-implicated variant(s)
     
    Phenotypic Data
    Phenotypic Class
    Phenotype Manifest In
    Detailed Description
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    External Data
    Interactions
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    Phenotypic Class
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    Complementation and Rescue Data
    Comments
    Images (0)
    Mutant
    Wild-type
    Stocks (0)
    Notes on Origin
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    External Crossreferences and Linkouts ( 0 )
    Synonyms and Secondary IDs (1)
    Reported As
    Symbol Synonym
    CG5674btv-4
    Name Synonyms
    Secondary FlyBase IDs
      References (1)