FB2024_03 , released June 25, 2024
Allele: Dmel\lncRNA:CR45362KO
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General Information
Symbol
Dmel\lncRNA:CR45362KO
Species
D. melanogaster
Name
FlyBase ID
FBal0367972
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Mutagen
Nature of the Allele
Progenitor genotype
Cytology
Description

Deletion of the second exon of lncRNA:CR45362.

Deletion spanning 1675bp, including excision of 770bp from the lncRNA:CR45362 gene. Also insertion of 15bp (GGGAAAACCAACTGA), likely the result of NHEJ repair.

Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Comment:

Deletion spanning 1675bp, including excision of 770bp from CR45362 gene.

Inserted_sequence:

GGGAAAACCAACTGA

Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

In lncRNA:CR45362KO homozygous males, the seminal vesicle is devoid of sperm. During individualization, spermatid nuclei are elongated but, unlike controls, are dispersed and not bundled together; the actin cones of the individualization complex are not properly formed.

External Data
Interactions
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Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
CR45362Δ1
lncRNA:CR45362KO
Name Synonyms
Secondary FlyBase IDs
    References (2)