FB2024_03 , released June 25, 2024
Allele: Dmel\E2f1ΔRA
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General Information
Symbol
Dmel\E2f1ΔRA
Species
D. melanogaster
Name
FlyBase ID
FBal0361163
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
de2f1ΔRA
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Associated Insertion(s)
Cytology
Description

FLP-mediated recombination between the two progenitor insertions (PBac{WH}E2f1f05222 and P{XP}E2f1d01508) has deleted the intervening genomic sequence, removing the exon that encodes the 5'UTR of the E2f1 RA, RD and RE isoforms; the deletion extends from 35bp upstream to 2857bp downstream of the RA/RE isoform transcription start site. A hybrid residual element remains at the site of the deletion.

Allele components
Component
Use(s)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Comment:

FLP-mediated recombination between the two progenitor insertions has deleted sequence extending from 35bp upstream to 2857bp downstream of the exon that encodes the 5'UTR of the E2f1 RA, RD and RE isoforms. A hybrid residual element that contains 645bp of P{XP}E2f1d01508) and 1342bp of PBac{WH}E2f1f05222 remains at the site of the deletion.

Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference
External Data
Interactions
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Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
Name Synonyms
Secondary FlyBase IDs
    References (2)