FB2024_03 , released June 25, 2024
Allele: Ecol\lexAp65.ple
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General Information
Symbol
Ecol\lexAp65.ple
Species
E. coli
Name
FlyBase ID
FBal0346143
Feature type
allele
Associated gene
Ecol\lexA
Associated Insertion(s)
Carried in Construct
P{ple-lexA::p65}
Also Known As
TH-LexA, TH-LexAp65
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Galili et al., 2014)
Progenitor genotype
Carried in construct
P{ple-lexA::p65}
Cytology
Description

ple regulatory sequence (the same as present in Scer\GAL4ple.PF) controls expression of the lexA::p65 driver. The ple sequence comprises a 4.1kb fragment of ple sequence from upstream of the transcription start site (this is fused upstream of lexA::p65) and a 6.9kb fragment that includes the ple coding region (this is fused downstream of lexA::p65 and an Hsp70 termination signal, so that regulatory sequences present in the ple coding region are included, but the ple coding sequence is not translated).

(Galili et al., 2014)
Allele components
Component
Use(s)
Regulatory region(s)
ple
Encoded product / tool
lexA::p65
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      distribution deduced from reporter (Gal4 UAS)
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      adult stage
      dopaminergic PPL1 neuron
      (Kim et al., 2017)
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      ple
      (Kim et al., 2017)
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Ecol\lexAp65.ple
      Name Synonyms
      Secondary FlyBase IDs
        References (5)