Inhibition (using Hsap\KCNJ2lexAop.cHa) of Ecol\lexAp65.Ilp7.DP cells in larvae significantly reduces nociceptive movement responses following stimulation with a von Frey filament, compared to controls.
Optogenetic activation (using Cnoc\ChR1::Csub\ChRCsChrimson.IVS.13XLexAop2.Venus with 625 nm (red) light) of Ecol\lexAp65.Ilp7.DP cells in larvae significantly increases nociceptive movement responses following stimulation with a von Frey filament, compared to controls.
Ecol\lexAp65.Ilp7.DP/Hsap\KCNJ2lexAop.cHa is a non-enhancer of abnormal locomotor behavior | larval stage | conditional phenotype of Cnoc\ChR1::Csub\ChRCsChrimson.IVS.20xUAS.Venus, Scer\GAL4GMR82E12
Ecol\lexAp65.Ilp7.DP/Hsap\KCNJ2lexAop.cHa is a non-suppressor of abnormal locomotor behavior | larval stage | conditional phenotype of Cnoc\ChR1::Csub\ChRCsChrimson.IVS.20xUAS.Venus, Scer\GAL4GMR82E12