FB2024_03 , released June 25, 2024
Allele: Dmel\GATAe2
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General Information
Symbol
Dmel\GATAe2
Species
D. melanogaster
Name
FlyBase ID
FBal0344480
Feature type
allele
Associated gene
Dmel\GATAe
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
CRISPR/Cas9
(Hernández de Madrid and Casanova, 2018)
Progenitor genotype
Cytology
Description

Mutation within the first common exon of GATAe, resulting in an early stop codon in all transcript isoforms (predicted to result in a truncated protein of 45 amino acids).

(Hernández de Madrid and Casanova, 2018)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
delins
3R:16,016,308..16,016,317 [+]
Inserted_sequence:

ATTCAGGCTCTG

Comment:

TCAGGCTCTA becomes ATTCAGGCTCTG at this location. This leads to an early stop codon in all isoforms and a truncated polypeptide of 30 or 45 amino acids depending on the isoform.

(Hernández de Madrid and Casanova, 2018)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      GATAe2 mutant embryos do not show morphological abnormalities in the midgut.

      (Hernández de Madrid and Casanova, 2018)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      grn7L GATAe2 double mutant embryos do not show morphological abnormalities in the midgut.

      (Hernández de Madrid and Casanova, 2018)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      GATAe2
      dGATAe2
      (Hernández de Madrid and Casanova, 2018)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)