FB2024_03 , released June 25, 2024
Allele: Ecol\lexAdsx-lexA::p65
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General Information
Symbol
Ecol\lexAdsx-lexA::p65
Species
E. coli
Name
FlyBase ID
FBal0343781
Feature type
allele
Associated gene
Ecol\lexA
Associated Insertion(s)
TI{lexA::p65}dsxlexA::p65
Carried in Construct
Also Known As
dsxlexA, dsx-LexA, dsxLexA::p65
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ends-out gene targeting
(Zhou et al., 2015)
FLPase
(Zhou et al., 2015)
I-SceI
(Zhou et al., 2015)
Progenitor genotype
Associated Insertion(s)
TI{lexA::p65}dsxlexA::p65
Cytology
Description

The coding sequence of dsx exon 2 is replaced with the coding sequence for lexA::p65 followed by a stop codon and a transcription stop cassette containing the SV40 poly-A sequence in tandem with the αTub84B 3' UTR.

(Zhou et al., 2015)
Allele components
Component
Use(s)
Inserted element
TI{lexA::p65}
Encoded product / tool
lexA::p65
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      distribution deduced from reporter (Gal4 UAS)
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      adult stage
      adult doublesex TN1A (male) neuron
      (Shirangi et al., 2016)
      adult doublesex msB TN2 (male) neuron
      (Shirangi et al., 2016)
      adult fruitless P1 (male) neuron

      Comment: A FLP/FRT strategy shows TI{lexA::p65}dsxlexA::p65 drives expression in adult ingestion neuron 1 when combined with TI{GAL4::p65}CCKLR-17D3GAL4::p65.

      (Wu et al., 2019)
      Additional Information
      Statement
      Reference

      In combination with ScerGAL4VT017258RA.

      (Shirangi et al., 2016)
       
      Marker for
      Reflects expression of
      dsx
      (Shirangi et al., 2016)
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      Ecol\lexAdsx-lexA::p65
      dsxLexA::p65
      (Shirangi et al., 2016, Zhou et al., 2015)
      dsxLexA
      (Wu et al., 2019)
      dsxlexA
      (Zhou et al., 2015)
      Name Synonyms
      Secondary FlyBase IDs
        References (9)