FB2024_03 , released June 25, 2024
Allele: Dmel\Mzt1sfGFP
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General Information
Symbol
Dmel\Mzt1sfGFP
Species
D. melanogaster
Name
FlyBase ID
FBal0343279
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Progenitor genotype
Associated Insertion(s)
Cytology
Description

A sfGFP tag has been introduced into the endogenous Mzt1 locus.

Allele components
Component
Use(s)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
distribution deduced from reporter or direct label
Stage
Tissue/Position (including subcellular localization)
Reference
Additional Information
Statement
Reference

Colocalization studies with gamma tubulin show that Mzt1 reporter is present at low leves in early spermatocytes and in higher levels in mature spermatocytes where it localizes in centrioles. It concentrates strongly at basal bodies in round spermatids. It localizes along the length of the basal body and at the centriole adjunct which forms a ring around the centre of the basal body in elongating spermatids and in intermediate spermatids. In late canoe-stage nuclei, it has started to dissociate from the basal body.

 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
Mzt1sfGFP
Name Synonyms
Secondary FlyBase IDs
    References (1)