FB2024_03 , released June 25, 2024
Allele: Dmel\dapUASp.EGFP
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General Information
Symbol
Dmel\dapUASp.EGFP
Species
D. melanogaster
Name
FlyBase ID
FBal0323610
Feature type
allele
Associated gene
Dmel\dap
Associated Insertion(s)
Carried in Construct
P{UASp-EGFP-dap.WT}
Key Links
Transgenic product class
wild_type
(Swanson et al., 2015)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Swanson et al., 2015)
Mutagen
in vitro construct
(Swanson et al., 2015)
Progenitor genotype
Carried in construct
P{UASp-EGFP-dap.WT}
Cytology
Description

UASp regulatory sequences drive expression of wild-type dap that is tagged at the N-terminal end with EGFP.

(Swanson et al., 2015)
Allele components
Component
Use(s)
Regulatory region(s)
UASp
Encoded product / tool
dap
Tagged with
EGFP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of dapScer\UAS.P\T.T:Avic\GFP-EGFP under the control of Scer\GAL4prd.PU does not interfere with the normal cell cycle program of embryonic epidermal cells or on the endocycle progression of embryonic midgut cells. Scer\GAL4αTub84B.PL-driven expression also has no effect on the proliferation or differentiation of central and peripheral nervous system. dapScer\UAS.P\T.T:Avic\GFP-EGFP expression under the Scer\GAL4en.PU driver does not disrupt growth or proliferation of the imaginal wing disc cells or - with the Scer\GAL4ptc-559.1 driver, the endocycle program in the salivary gland cells in third instar larvae. However, expression under the Scer\GAL4c323 driver does disrupt the endocycle progression in the ovarian follicle cells.

      (Swanson et al., 2015)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      dapScer\UAS.P\T.T:Avic\GFP-EGFP
      dapUASp.EGFP
      Name Synonyms
      Secondary FlyBase IDs
        References (1)