E58Y
Analagous codon mutation in human FIG4 implicated in ALS11; mutation carried on in vitro construct; site of nucleotide substitution in fly gene inferred by FlyBase curator based on reported amino acid change.
FIG4D53Y.UAS.Tag:MYC/Scer\GAL4Mef2.PU partially rescues FIG4Δ1
Expression of FIG4D53Y.Scer\UAS.T:Hsap\MYC under the control of Scer\GAL4Mef2.PU partially rescues the lysosome expansion phenotype in somatic muscles of FIG4Δ1 homozygous third instar larvae.