FB2024_03 , released June 25, 2024
Allele: Dmel\Gas41NP2248
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General Information
Symbol
Dmel\Gas41NP2248
Species
D. melanogaster
Name
FlyBase ID
FBal0322772
Feature type
allele
Associated gene
Dmel\Gas41
Associated Insertion(s)
P{GawB}Gas41NP2248
Carried in Construct
Key Links
Genomic Maps

Allele class

hypomorphic allele - molecular evidence

Mutagen
    Nature of the Allele
    Allele class

    hypomorphic allele - molecular evidence

    (Gandhi et al., 2015)
    Mutagen
    Progenitor genotype
    Associated Insertion(s)
    P{GawB}Gas41NP2248
    Cytology
    Description
    Allele components
    Component
    Use(s)
    Inserted element
    P{GawB}
    Encoded product / tool
    GAL4
    Mutations Mapped to the Genome
    Curation Data
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        Gas41NP2248 homozygotes die at first larval instar stage.

        Combination with a single copy of Gas41NP2248 also partially suppresses the variegation of the short scutellar bristle phenotype characteristic for T(2;3)SbV adults leading to a significantly higher proportion of short (stubble) bristles than in T(2;3)SbV alone.

        (Gandhi et al., 2015)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Suppressor of
        Statement
        Reference

        Gas41[+]/Gas41NP2248 is a suppressor | partially of abnormal eye color phenotype of wRNAi.GMR.cGa

        (Gandhi et al., 2015)

        Gas41[+]/Gas41NP2248 is a suppressor | partially of visible | adult stage phenotype of wRNAi.GMR.cGa

        (Gandhi et al., 2015)

        Gas41f05565/Gas41NP2248 is a suppressor | partially of abnormal eye color phenotype of wRNAi.GMR.cGa

        (Gandhi et al., 2015)

        Gas41f05565/Gas41NP2248 is a suppressor | partially of visible | adult stage phenotype of wRNAi.GMR.cGa

        (Gandhi et al., 2015)
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference

        Combination of wdsRNA.GMR.cGa with Gas41f05565 or Gas41NP2248 individually in heterozygous or together in transheterozygous state, significantly ameliorates the loss of pigmentation in the adult eye induced by the wdsRNA.GMR.cGa RNAi.

        (Gandhi et al., 2015)
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (2)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (2)
        Reported As
        Symbol Synonym
        Gas41NP2248
        Gas41Np2248
        (Gandhi et al., 2015)
        Name Synonyms
        Secondary FlyBase IDs
          References (1)