UAS regulatory sequences drive expression of Cprd\ΒPDH-II coding sequences.
Expression of Zzzz\ΒPDH-IIScer\UAS.cBa in the PDF circuit under the control of Scer\GAL4P2.4.Pdf, in a homozygous Pdf01 mutant background, only modestly improves the rhythmicity, with the flies displaying a unconsolidated activity profile. In addition, these flies show a short circadian period, reminiscent of Pdf01 mutant flies.
Expression of Zzzz\ΒPDH-IIScer\UAS.cBa in the PDF circuit under the control of Scer\GAL4P2.4.Pdf fails to suppress the modest morning peak and an evening peak of activity that's found in Pdf01 mutants.