Deletion of residues 18-261 of the ktub coding region. A loxP cassette which contains the Scer\GAL4 coding sequence and a w+mW.hs marker has been inserted in place of the deleted ktub sequence. The Scer\GAL4 sequence is not expressed in this mutant allele.
ktubG/ktubG or ktub1/ktubG flies show significant locomotor defects (reduced climbing ability) compared to wild type. ktubG/ktubG flies show a significant reduction in sound evoked potentials from the antennal nerve compared to wild type.