FB2024_03 , released June 25, 2024
Allele: Scer\GAL4NP7506
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General Information
Symbol
Scer\GAL4NP7506
Species
S. cerevisiae
Name
FlyBase ID
FBal0316350
Feature type
allele
Associated gene
Scer\GAL4
Associated Insertion(s)
P{GawB}NP7506
Carried in Construct
Also Known As
NP7506-Gal4
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Associated Insertion(s)
    P{GawB}NP7506
    Cytology
    Description
    Allele components
    Component
    Use(s)
    Inserted element
    P{GawB}
    Encoded product / tool
    GAL4
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        distribution deduced from reporter (Gal4 UAS)
        Stage
        Tissue/Position (including subcellular localization)
        Reference
        adult stage
        mechanosensory neuron | subset of pseudotracheal taste peg
        (Miyazaki and Ito, 2010)
        mechanosensory neuron | subset of mechanosensory labral sensillum
        (Miyazaki and Ito, 2010)
        chemosensory neuron | subset of adult labellum sensillum
        (Miyazaki and Ito, 2010)
        sensory neuron | subset of maxillary palp | faint
        (Miyazaki and Ito, 2010)
        mechanosensory neuron | subset of anterior maxillary sensory center
        (Miyazaki and Ito, 2010)
        mechanosensory neuron | subset of labial sensory center
        (Miyazaki and Ito, 2010)
        Additional Information
        Statement
        Reference

        ScerGAL4NP7506 drives expression in mechanosensory neurons in around two-thirds of labellar pseudotracheal taste pegs which project to the AMS2 and AMS3 regions of the anterior maxillary sensory center and the LS3 region of the labial sensory center. Expression is also observed in the two mechanosensory bristles on the lateral surface. Faint labeling is detected in some neurons of the maxillary palpus.

        (Miyazaki and Ito, 2010)
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        Optogenetic activation (using Cnoc\ChR1::Csub\ChRCsChrimson.IVS.20xUAS.Venus with 617 nm (red) light) of Scer\GAL4NP7506 cells in adults results in induction of proboscis retraction due to stimulation during feeding, compared to controls; there is no induction of labellar spread, compared to controls.

        Inhibition (using Ctet\tetXTNT-LC.UAS) of Scer\GAL4NP7506 cells in adults, does not affect responses of Scer\GAL4GMR58H01-expressing motor neurons to labellar caffeine application, compared to controls.

        (Zhou et al., 2019)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        NOT Enhancer of
        NOT Suppressor of
        Additional Comments
        Genetic Interactions
        Statement
        Reference
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (1)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (1)
        Reported As
        Symbol Synonym
        Scer\GAL4NP7506
        Name Synonyms
        Secondary FlyBase IDs
          References (3)