FB2024_03 , released June 25, 2024
Allele: Dmel\Hr3MI04877-TG4.no-pA.1
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General Information
Symbol
Dmel\Hr3MI04877-TG4.no-pA.1
Species
D. melanogaster
Name
FlyBase ID
FBal0304212
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Nature of the Allele
Allele class
Progenitor genotype
Cytology
Description

The attP cassette in the Mi{MIC}Hr46MI04877 insertion has been replaced with a Trojan GAL4 cassette that contains a splice acceptor site followed by the T2A peptide and the Scer\GAL4 coding sequence. The insertion is in the correct orientation to gene trap Hr46. The splice acceptor ensures that the T2A-Scer\GAL4 open reading frame is incorporated into the Hr46 mRNA, while the T2A sequence is expected to truncate the native Hr46 gene product and promotes the separate translation of the Scer\GAL4 open reading frame. Thus Scer\GAL4 expression is driven by the native Hr46 regulatory sequences.

Allele components
Component
Use(s)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
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Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
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Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
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Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
Hr3MI04877-TG4.no-pA.1
Hr46MI04877-TG4.no-pA.1
Name Synonyms
Secondary FlyBase IDs
    References (1)