FB2024_03 , released June 25, 2024
Allele: Ecol\lexAVP16.ort.C1a
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General Information
Symbol
Ecol\lexAVP16.ort.C1a
Species
E. coli
Name
FlyBase ID
FBal0296554
Feature type
allele
Associated gene
Ecol\lexA
Associated Insertion(s)
Carried in Construct
P{ort-lexA.C1a.VP16}
Also Known As
ortC1a-LexA::VP16
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Ting et al., 2014)
Progenitor genotype
Carried in construct
P{ort-lexA.C1a.VP16}
Cytology
Description

The ortC1a enhancer and hs43 mini-promoter regulate expression of a lexA::VP16 driver.

(Ting et al., 2014)
Allele components
Component
Use(s)
Regulatory region(s)
ort
Encoded product / tool
lexA::VP16
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      distribution deduced from reporter (Gal4 UAS)
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      adult stage
      transmedullary neuron Tm5a
      (Ting et al., 2014)
      transmedullary neuron Tm5b
      (Ting et al., 2014)
      transmedullary neuron Tm5c
      (Ting et al., 2014)
      transmedullary neuron Tm20
      (Ting et al., 2014)
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      ort
      (Ting et al., 2014)
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Inhibition (using Ctet\tetXTNT-LC.13x.lexAop.Tag:HA) of Ecol\lexAVP16.ort.C1a cells in adults results in a significant reduction in short-term aversive visual (blue/green) memory, compared to controls, with no effect on the optomotor response to blue-green patterns.

      (Melnattur et al., 2014)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Ecol\lexAVP16.ort.C1a
      Ecol\lexAort.C1a.T:Hsim\VP16
      Name Synonyms
      Secondary FlyBase IDs
        References (6)